Skip to main content
This website uses cookies to ensure you get the best experience. By continuing to use this site, you agree to the use of cookies.

Please note: Your browser does not support the features used on Addgene's website. You may not be able to create an account or request plasmids through this website until you upgrade your browser. Learn more

Please note: Your browser does not fully support some of the features used on Addgene's website. If you run into any problems registering, depositing, or ordering please contact us at [email protected]. Learn more

Addgene
Spatiotemporal control of fibroblast growth factor receptor signals by blue light.
Kim N, Kim JM, Lee M, Kim CY, Chang KY, Heo WD
Chem Biol. 2014 Jul 17;21(7):903-12. doi: 10.1016/j.chembiol.2014.05.013. Epub 2014 Jun 26. PubMed Article

Plasmids from Article

ID Plasmid Purpose
59776pCMV-OptoFGFR1Expresses myristoylation signal peptide-FGFR1 cytoplasmic region-PHR domain of cryptochrome2-mCitrine fused protein
59777pCMV-OptoFGFR1-Y766FExpresses optoFGFR1 with mutation in PLC-gamma binding phosphotyrosine site of FGFR1
59778pCMV-OptoFGFR1-D387AExpresses optoFGFR1 with mutation in PHR to suppress homointeraction, thus cannot be activated by light

Antibodies from Article