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Dynamic switching of active promoter and enhancer domains regulates Tet1 and Tet2 expression during cell state transitions between pluripotency and differentiation.
Sohni A, Bartoccetti M, Khoueiry R, Spans L, Vande Velde J, De Troyer L, Pulakanti K, Claessens F, Rao S, Koh KP
Mol Cell Biol. 2015 Mar 15;35(6):1026-42. doi: 10.1128/MCB.01172-14. Epub 2015 Jan 12.
PubMed Article

Plasmids from Article

ID Plasmid Purpose  
63879pGL3-Tet2 promoter FLuciferase reporter plasmid used to study transcriptional control of murine Tet2
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63880pGL3-SV40P-Tet1 enhancer ELuciferase reporter plasmid used to study transcriptional control of murine Tet1
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63881pGL3-Tet1 promoter ALuciferase reporter plasmid used to study transcriptional control of murine Tet1
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63882pGL3-Tet1 promoter BLuciferase reporter plasmid used to study transcriptional control of murine Tet1
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63883pGL3-SV40P-Tet2 enhancer H1Luciferase reporter plasmid used to study transcriptional control of murine Tet2
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Antibodies from Article