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Joan Massague Lab Plasmids

The Joan Massague Lab has deposited plasmids at Addgene for distribution to academic researchers. Addgene is a non-profit plasmid repository dedicated to improving life science research.

Learn more about research in the Joan Massague Lab.

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Title Authors
Ubiquitin ligase Nedd4L targets activated Smad2/3 to limit TGF-beta signaling. Gao et al
Nuclear CDKs drive Smad transcriptional activation and turnover in BMP and TGF-beta pathways. Alarcon et al
WNT/TCF signaling through LEF1 and HOXB9 mediates lung adenocarcinoma metastasis. Nguyen et al
Latent bone metastasis in breast cancer tied to Src-dependent survival signals. Zhang et al
Genes that mediate breast cancer metastasis to the brain. Bos et al
TGFbeta primes breast tumors for lung metastasis seeding through angiopoietin-like 4. Padua et al
Endogenous human microRNAs that suppress breast cancer metastasis. Tavazoie et al
ID genes mediate tumor reinitiation during breast cancer lung metastasis. Gupta et al
Genome-wide impact of the BRG1 SWI/SNF chromatin remodeler on the transforming growth factor beta transcriptional program. Xi et al
C/EBPbeta at the core of the TGFbeta cytostatic response and its evasion in metastatic breast cancer cells. Gomis et al
Hematopoiesis controlled by distinct TIF1gamma and Smad4 branches of the TGFbeta pathway. He et al
TGF-beta directly targets cytotoxic T cell functions during tumor evasion of immune surveillance. Thomas et al
Breast cancer bone metastasis mediated by the Smad tumor suppressor pathway. Kang et al
Integration of Smad and forkhead pathways in the control of neuroepithelial and glioblastoma cell proliferation. Seoane et al
Mad upregulation and Id2 repression accompany transforming growth factor (TGF)-beta-mediated epithelial cell growth suppression. Siegel et al
Transforming growth factor beta signaling impairs Neu-induced mammary tumorigenesis while promoting pulmonary metastasis. Siegel et al
E2F4/5 and p107 as Smad cofactors linking the TGFbeta receptor to c-myc repression. Chen et al
Defective repression of c-myc in breast cancer cells: A loss at the core of the transforming growth factor beta growth arrest program. Chen et al
OAZ uses distinct DNA- and protein-binding zinc fingers in separate BMP-Smad and Olf signaling pathways. Hata et al
Multiple modes of repression by the Smad transcriptional corepressor TGIF. Wotton et al
Ubiquitin-dependent degradation of TGF-beta-activated smad2. Lo et al
A mechanism of repression of TGFbeta/ Smad signaling by oncogenic Ras. Kretzschmar et al
Smad6 inhibits BMP/Smad1 signaling by specifically competing with the Smad4 tumor suppressor. Hata et al
Dual role of the Smad4/DPC4 tumor suppressor in TGFbeta-inducible transcriptional complexes. Liu et al
Mutations increasing autoinhibition inactivate tumour suppressors Smad2 and Smad4. Hata et al
The TGF-beta family mediator Smad1 is phosphorylated directly and activated functionally by the BMP receptor kinase. Kretzschmar et al
Partnership between DPC4 and SMAD proteins in TGF-beta signalling pathways. Lagna et al
A human Mad protein acting as a BMP-regulated transcriptional activator. Liu et al
Activation of signalling by the activin receptor complex. Attisano et al
Human type II receptor for bone morphogenic proteins (BMPs): extension of the two-kinase receptor model to the BMPs. Liu et al
Cell-cycle inhibition by independent CDK and PCNA binding domains in p21Cip1. Luo et al
TGF beta signals through a heteromeric protein kinase receptor complex. Wrana et al
Joan Massague lab plasmids