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Reference Icon Redbook Fluorescent Proteins: Activity Regulation


Background

GFP_activity_regulation.jpg

Fluorescent proteins such as GFP have long been used for labeling, but new methods are emerging to use these fluorescent proteins to modulate biological activity. Early tools allow scientists to regulate transcription, and additional tools are being developed to regulate a variety of other activities. By using GFP as a scaffold, scientists can design de novo systems using modular components or take advantage of existing GFP-lines for cell-specific manipulation.

Plasmids

Fluorescent Protein Purpose Principal Investigator Plasmids
GFP GFP-dependent transcription factors Connie Cepko See Plasmids
Dronpa Optical control of protein activity Michael Lin See Plasmids

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