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Tat competes with CIITA for the binding to P-TEFb and blocks the expression of MHC class II genes in HIV infection.

Kanazawa S, Okamoto T, Peterlin BM
Immunity. 2000 Jan . 12(1):61-70. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
14650pcDNA3 myc CIITA (P#808)
14651pCol2 flu CIITA (P#294)

Antibodies from Article