LOCUS       sequence-10679-e        2439 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 2439)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 2439)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-MAP4K2
FEATURES             Location/Qualifiers
     source          1..2439
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 atggcgctgc tgcgggatgt gtcgctgcag gacccgcggg accgcttcga gctgctgcag
       61 cgcgtggggg ccgggaccta tggcgacgtc tacaaggccc gcgacacggt cacgtccgaa
      121 ctggccgccg tgaagatagt caagctagac ccaggggacg acatcagctc cctccagcag
      181 gaaatcacca tcctgcgtga gtgccgccac cccaatgtgg tggcctacat tggcagctac
      241 ctcaggaatg accgcttgtg gatctgcatg gagttctgcg gagggggctc cctgcaggag
      301 atttaccatg ccactgggcc cctggaggag cggcagattg cctacgtctg ccgagaggca
      361 ctgaaggggc tccaccacct gcattctcag gggaagatcc acagagacat caagggagcc
      421 aaccttctcc tcactctcca gggagatgtc aaactggctg actttggggt gtcaggcgag
      481 ctgacagcgt ctgtggccaa gaggaggtct ttcattggga ctccctactg gatggctccc
      541 gaggtggctg ctgtggagcg caaaggtggc tacaatgagc tatgtgacgt ctgggccctg
      601 ggcatcactg ccattgagct gggcgagctg cagccccctc tgttccacct gcaccccatg
      661 agggccctga tgctcatgtc gaagagcagc ttccagccgc ccaaactgag agataagact
      721 cgctggaccc agaatttcca ccactttctc aaactggccc tgaccaagaa tcctaagaag
      781 aggccgacag cagagaagct cctgcagcac ccgttcacga ctcagcagct ccctcgggcc
      841 ctcctcacac agctgctgga caaagccagt gaccctcatc tggggacccc ctcccctgag
      901 gactgtgagc tggagaccta tgacatgttt ccagacacca ttcactcccg ggggcagcac
      961 ggcccagccg agaggacccc ctcggagatc cagtttcacc aggtgaaatt tggcgcccca
     1021 cgcaggaagg aaactgaccc actgaatgag ccgtgggagg aagagtggac actactggga
     1081 aaggaagagt tgagtgggag cctgctgcag tcggtccagg aggccctgga ggaaaggagt
     1141 ctgactattc ggtcagcctc agaattccag gagctggact ccccagacga taccatggga
     1201 accatcaagc gggccccgtt cctagggcca ctccccactg accctccagc agaggagcct
     1261 ctgtccagtc ccccaggccc caacagctcc ccactgctgc ccacggcctg ggccaccatg
     1321 aagcagcggg aggatcctga gaggtcatcc tgccacgggc tccccccaac tcccaaggtg
     1381 catatgggcg cctgcttctc caaggtcttc aatggctgcc ccctgcggat ccacgctgct
     1441 gtcacctgga ttcaccctgt tactcgggac cagttcctgg tggtaggggc cgaggaaggc
     1501 atctacacac tcaacctgca tgaactgcat gaggatacgc tggagaagct gatttcacat
     1561 cgctgctcct ggctctactg cgtgaacaac gtgctgctgt cactctcagg gaaatccacg
     1621 cacatctggg cccatgacct cccaggcctg tttgagcagc ggaggctaca gcaacaggtt
     1681 cccctctcca tccccaccaa ccgcctcacc cagcgcatca tccccaggcg ctttgctctg
     1741 tccaccaaga ttcctgacac caaaggctgc ttgcagtgtc gtgtggtgcg gaatccctac
     1801 acgggtgcca ccttcctgct ggccgccctg cccaccagcc tgctcctgct gcagtggtat
     1861 gagccgctgc agaagtttct gctgctgaag aacttctcca gccctctgcc cagcccagct
     1921 gggatgctgg agccgctggt gctggatggg aaggagctgc cgcaggtgtg tgttggggcc
     1981 gaggggcctg aggggcccgg ctgccgcgtc ctgttccatg tcctgcccct ggaggctggc
     2041 ctgacgcccg acatcctcat cccacctgag gggatcccag gctcggccca gcaggtgatc
     2101 caggtggaca gggacacaat cctagtcagc tttgaacgct gtgtgaggat tgtcaacatg
     2161 cagggcgagc ccacggccac actggcacct gagctgacct ttgatttccc catcgagact
     2221 gtggtgtgcc tgcaggacag tgtgctggcc ttctggagcc atgggatgca aggccgaagc
     2281 ctggatacca atgaggtgac ccaggagatc acagatgaaa caaggatctt ccgagtgctt
     2341 ggggcccaca gagacatcat cctggagagc attcccactg acaacccaga ggcgcacagc
     2401 aacctctaca tcctcacggg ccaccagagc acctactaa
//
