LOCUS       sequence-10680-e        2892 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 2892)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 2892)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-SH3BP4
FEATURES             Location/Qualifiers
     source          1..2892
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 atggcggctc agcggatccg agcggccaac tccaatggcc tccctcgctg caagtcagag
       61 gggaccctga ttgacctgag cgaagggttt tcagagacga gctttaatga catcaaagtg
      121 ccttctccca gtgccttgct cgtagacaac cccacacctt tcggaaatgc aaaggaagtg
      181 attgcgatca aggactattg ccccaccaac ttcaccacac tgaagttctc caagggcgac
      241 catctctacg tcttggacac atctggcggt gagtggtggt acgcacacaa caccaccgaa
      301 atgggctaca tcccctcctc ctatgtgcag cccttgaact accggaactc aacactgagt
      361 gacagcggta tgattgataa tcttccagac agcccagacg aggtagccaa ggagctggag
      421 ctgctcgggg gatggacaga tgacaaaaaa gtaccaggca gaatgtacag taataaccct
      481 ttctggaatg gggtccagac caatccattt ctgaatggga acgtgcccgt catgcccagc
      541 ctggatgagc tgaatcccaa aagtactgtg gatttgctcc tttttgacgc aggtacatcc
      601 tccttcaccg aatccagctc agccaccacg aatagcactg gcaacatctt cgatgagctt
      661 ccagtcacaa acggactcca cgcagagccg ccggtcaggc gggacaaccc cttcttcaga
      721 agcaagcgct cctacagtct ctcggaactc tccgtcctcc aagccaagtc cgatgctccc
      781 acatcgtcga gtttcttcac cggcttgaaa tcacctgccc ccgagcaatt tcagagccgg
      841 gaggattttc gaactgcctg gctaaaccac aggaagctgg cccggtcttg ccacgacctg
      901 gacttgcttg gccaaagccc tggttggggc cagacccaag ccgtggagac aaacatcgtg
      961 tgcaagctgg atagctccgg gggtgctgtc cagcttcctg acaccagcat cagcatccac
     1021 gtgcccgagg gccacgtcgc ccctggggag acccagcaga tctccatgaa agccctgctg
     1081 gaccccccgc tggagctcaa cagtgacagg tcctgcagca tcagccctgt gctggaggtc
     1141 aagctgagca acctggaggt gaaaacctct atcatcttgg agatgaaagt gtcagccgag
     1201 ataaaaaatg acctttttag caaaagcaca gtgggcctcc agtgcctgag gagcgactcg
     1261 aaggaagggc catatgtctc cgtcccgctc aactgcagct gtggggacac ggtccaggca
     1321 cagctgcaca acctggagcc ctgtatgtac gtggctgtcg tggcccatgg cccaagcatc
     1381 ctctaccctt ccaccgtgtg ggacttcatc aataaaaaag tcacagtggg tctctacggc
     1441 cctaaacaca tccacccatc cttcaagacg gtagtgacca tttttgggca tgactgtgcc
     1501 ccaaagacgc tcctggtcag cgaggtcaca cgccaggcac ccaaccctgc cccggtggcc
     1561 ctgcagctgt gggggaagca ccagttcgtt ttgtccaggc cccaggatct caaggtctgt
     1621 atgttttcca atatgacgaa ttacgaggtc aaagccagcg agcaggccaa agtggtgcga
     1681 ggattccagc tgaagctggg caaggtgagc cgcctgatct tccccatcac ctcccagaac
     1741 cccaacgagc tctctgactt cacgctgcgg gttcaggtga aggacgacca ggaggccatc
     1801 ctcacccagt tttgtgtcca gactcctcag ccacccccta aaagtgccat caagccttcc
     1861 gggcaaagga ggtttctcaa gaagaacgaa gtcgggaaaa tcatcctgtc cccgtttgcc
     1921 accactacaa agtacccgac tttccaggac cgcccggtgt ccagcctcaa gtttggtaag
     1981 ttgctcaaga ctgtggtgcg gcagaacaag aaccactacc tgctggagta caagaagggc
     2041 gacgggatcg ccctgctcag cgaggagcgg gtcaggctcc ggggccagct gtggaccaag
     2101 gagtggtaca tcggctacta ccagggcagg gtgggcctcg tgcacaccaa gaacgtgctg
     2161 gtggtcggca gggcccggcc cagcctgtgc tcgggccccg agctgagcac ctcggtgctg
     2221 ctggagcaga tcctgcggcc ctgcaaattc ctcacgtaca tctatgcctc cgtgaggacc
     2281 ctgctcatgg agaacatcag cagctggcgc tccttcgctg acgccctggg ctacgtgaac
     2341 ctgccgctca cctttttctg ccgggcagag ctggatagtg agcccgagcg ggtggcgtcc
     2401 gtcctagaaa agctgaagga ggactgtaac aacactgaga acaaagaacg gaagtccttc
     2461 cagaaggagc ttgtgatggc cctactgaag atggactgcc agggcctggt ggtcagactc
     2521 atccaggact ttgtgctcct gaccacggct gtagaggtgg cccagcgctg gcgggagctg
     2581 gctgagaagc tggccaaggt ctccaagcag cagatggacg cctacgagtc tccccaccgg
     2641 gacaggaacg gggttgtgga cagcgaggcc atgtggaagc ctgcgtatga cttcttactc
     2701 acctggagcc atcagatcgg ggacagctac cgggatgtca tccaggagct gcacctgggc
     2761 ctggacaaga tgaaaaaccc catcaccaag cgctggaagc acctcactgg gactctgatc
     2821 ttggtgaact ccctggacgt tctgagagca gccgccttca gccctgcgga ccaggacgac
     2881 ttcgtgattt ga
//
