LOCUS       sequence-10683-e        2094 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 2094)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 2094)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-PRKCG
FEATURES             Location/Qualifiers
     source          1..2094
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     CDS             complement(1657..1668)
                     /codon_start=1
                     /product="Factor Xa recognition and cleavage site"
                     /label=Factor Xa site
                     /translation="IEGR"
ORIGIN
        1 atggctggtc tgggccccgg cgtaggcgat tcagaggggg gaccccggcc cctgttttgc
       61 agaaaggggg ccctgaggca gaaggtggtc cacgaagtca agagccacaa gttcaccgct
      121 cgcttcttca agcagcccac cttctgcagc cactgcaccg acttcatctg gggtatcgga
      181 aagcagggcc tgcaatgtca agtctgcagc tttgtggttc atcgacgatg ccacgaattt
      241 gtgaccttcg agtgtccagg cgctgggaag ggcccccaga cggatgaccc ccggaacaaa
      301 cacaagttcc gcctgcatag ctacagcagc cccaccttct gcgaccactg tggctccctc
      361 ctctacgggc ttgtgcacca gggcatgaaa tgctcctgct gcgagatgaa cgtgcaccgg
      421 cgctgtgtgc gtagcgtgcc ctccctgtgc ggtgtggacc acaccgagcg ccgcgggcgc
      481 ctgcagctgg agatccgggc tcccacagca gatgagatcc acgtaactgt tggcgaggcc
      541 cgtaacctaa ttcctatgga ccccaatggt ctctctgatc cctatgtgaa actgaagctc
      601 atcccagacc ctcggaacct gacgaaacag aagacccgaa cggtgaaagc cacgctaaac
      661 cctgtgtgga atgagacctt tgtgttcaac ctgaagccag gggatgtgga gcgccggctc
      721 agcgtggagg tgtgggactg ggaccggacc tcccgcaacg acttcatggg ggccatgtcc
      781 tttggcgtct cggagctgct caaggcgccc gtggatggct ggtacaagtt actgaaccag
      841 gaggagggcg agtattacaa tgtgccggtg gccgatgctg acaactgcag cctcctccag
      901 aagtttgagg cttgtaacta ccccctggaa ttgtatgagc gggtgcggat gggcccctct
      961 tcctctccca tcccctcccc ttcccctagt cccaccgacc ccaagcgctg cttcttcggg
     1021 gcgagtccag gacgcctgca catctccgac ttcagcttcc tcatggttct aggaaaaggc
     1081 agttttggga aggtgatgct ggccgagcgc aggggctctg atgagctcta cgccatcaag
     1141 atcttgaaaa aggacgtgat cgtccaggac gacgatgtgg actgcacgct ggtggagaaa
     1201 cgtgtgctgg cgctgggggg ccggggtcct ggcggccggc cccacttcct cacccagctc
     1261 cactccacct tccagacccc ggaccgcctg tatttcgtga tggagtacgt caccggggga
     1321 gacttgatgt accacattca acagctgggc aagtttaagg agccccatgc agcgttctac
     1381 gcggcagaaa tcgctatcgg cctcttcttc cttcacaatc agggcatcat ctacagggac
     1441 ctgaagctgg acaatgtgat gctggatgct gagggacaca tcaagatcac tgactttggc
     1501 atgtgtaagg agaacgtctt ccccgggacg acaacccgca ccttctgcgg gaccccggac
     1561 tacatagccc cggagatcat tgcctaccag ccctatggga agtctgtcga ttggtggtcc
     1621 tttggagttc tgctgtatga gatgttggca ggacagcctc ccttcgatgg ggaggacgag
     1681 gaggagctgt ttcaggccat catggaacaa actgtcacct accccaagtc gctttcccgg
     1741 gaagccgtgg ccatctgcaa ggggttcctg accaagcacc cagggaagcg cctgggctca
     1801 gggcctgatg gggaacctac catccgtgca catggctttt tccgctggat tgactgggag
     1861 cggctggaac gattggagat cccgcctcct ttcagacccc gcccgtgtgg ccgcagcggc
     1921 gagaactttg acaagttctt cacgcgggcg gcgccagcgc tgacccctcc agaccgccta
     1981 gtcctggcca gcatcgacca ggccgatttc cagggcttca cctacgtgaa ccccgacttc
     2041 gtgcacccgg atgcccgcag ccccaccagc ccagtgcctg tgcccgtcat gtaa
//
