LOCUS       sequence-10686-e        1416 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 1416)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 1416)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-MAPKAPK5
FEATURES             Location/Qualifiers
     source          1..1416
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 atgtcggagg agagcgacat ggacaaagcc atcaaggaaa cttccatttt agaagaatac
       61 agtatcaatt ggactcagaa gctgggagct ggaattagtg gtccagttag agtctgtgta
      121 aagaaatcta ctcaagaacg gtttgcgctg aaaattcttc ttgatcgtcc aaaagctaga
      181 aatgaggtac gtctgcacat gatgtgtgcc acacacccaa acatagttca gattattgaa
      241 gtgtttgcta acagtgtcca gtttccccat gagtccagcc ctagggcccg actcttaatt
      301 gtaatggaga tgatggaagg gggagagcta tttcacagaa tcagccagca ccggcacttt
      361 acagagaagc aagccagcca agtaacaaag cagatagctt tggctctgcg gcactgtcac
      421 ttgttaaaca ttgcgcacag agacctcaag cctgaaaatc tgctttttaa ggataactct
      481 ttggatgccc cagtgaagtt gtgtgacttt ggatttgcca agattgacca aggtgacttg
      541 atgacacccc agttcacccc ttattatgta gcaccccagg tactggaggc gcaaagaagg
      601 catcagaagg agaaatctgg catcatacct acctcaccga cgccctacac ttacaacaag
      661 agctgtgact tgtggtccct aggggtgatt atctatgtga tgctgtgcgg ataccctcct
      721 ttttactcca aacaccacag ccggactatc ccaaaggata tgcgaagaaa gatcatgaca
      781 ggcagttttg agttcccaga ggaagagtgg agtcagatct cagagatggc caaagatgtt
      841 gtgaggaagc tcctgaaggt caaaccggag gagagactca ccatcgaggg agtgctggac
      901 cacccctggc tcaattccac cgaggccctg gataatgtgc tgccttctgc tcagctgatg
      961 atggacaagg cagtggttgc aggaatccag caggctcacg cggaacagtt ggccaacatg
     1021 agaatccagg atctgaaagt cagcctcaaa cccctgcact cagtgaacaa ccccattctg
     1081 cggaagagga agttacttgg caccaagcca aaggacagtg tctatatcca cgaccatgag
     1141 aatggagccg aggattccaa tgttgccttg gaaaaactcc gagatgtgat tgctcagtgt
     1201 attctccccc aggctggaga gaatgaagat gagaaactga atgaagtaat gcaggaggct
     1261 tggaagtata accgggaatg caaactccta agagatactc tgcagagctt cagctggaat
     1321 ggtcgtggat tcacagataa agtagatcga ctaaaactgg cagaaattgt gaagcaggtg
     1381 atagaagagc aaaccacgtc ccacgaatcc caataa
//
