LOCUS       sequence-10708-e        1482 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 1482)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 1482)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-ACVR1C
FEATURES             Location/Qualifiers
     source          1..1482
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 atgacccggg cgctctgctc agcgctccgc caggctctcc tgctgctcgc agcggccgcc
       61 gagctctcgc caggactgaa gtgtgtatgt cttttgtgtg attcttcaaa ctttacctgc
      121 caaacagaag gagcatgttg ggcatcagtc atgctaacca atggaaaaga gcaggtgatc
      181 aaatcctgtg tctcccttcc agaactgaat gctcaagtct tctgtcatag ttccaacaat
      241 gttaccaaaa ccgaatgctg cttcacagat ttttgcaaca acataacact gcaccttcca
      301 acagcatcac caaatgcccc aaaacttgga cccatggagc tggccatcat tattactgtg
      361 cctgtttgcc tcctgtccat agctgcgatg ctgacagtat gggcatgcca gggtcgacag
      421 tgctcctaca ggaagaaaaa gagaccaaat gtggaggaac cactctctga gtgcaatctg
      481 gtaaatgctg gaaaaactct gaaagatctg atttatgatg tgaccgcctc tggatctggc
      541 tctggtctac ctctgttggt tcaaaggaca attgcaagga cgattgtgct tcaggaaata
      601 gtaggaaaag gtagatttgg tgaggtgtgg catggaagat ggtgtgggga agatgtggct
      661 gtgaaaatat tctcctccag agatgaaaga tattggtttc gtgaggcaga aatttaccag
      721 acggtcatgc tgcgacatga aaacatcctt ggtttcattg ctgctgacaa caaagataat
      781 ggaacttgga ctcaactttg gctggtatct gaatatcatg aacagggctc cttatatgac
      841 tatttgaata gaaatatagt gaccatggct ggaatgatca agctggcgct ctcaattgct
      901 agtggtctgg cacaccttca tatggagatt gttggtacac aaggtaaacc tgctattgct
      961 catcgagaca taaaatcaaa gaatatctta gtaaaaaagt gtgaaacttg tgccatagcg
     1021 gacttagggt tggctgtgaa gcatgattca atactgaaca ctatcgacat acctcagaat
     1081 cctaaagtgg gaaccaagag gtatatggct cctgaaatgc ttgatgatac aatgaatgtg
     1141 aatatctttg agtccttcaa acgagctgac atctattctg ttggtctggt ttactgggaa
     1201 atagcccgga ggtgttcagt cggaggaatt gttgaggagt accaattgcc ttattatgac
     1261 atggtgcctt cagatccctc gatagaggaa atgagaaagg ttgtttgtga ccagaagttt
     1321 cgaccaagta tcccaaacca gtggcaaagt tgtgaagcac tccgagtcat ggggagaata
     1381 atgcgtgagt gttggtatgc caacggagcg gcccgcctaa ctgctcttcg tattaagaag
     1441 actatatctc aactttgtgt caaagaagac tgcaaagcct aa
//
