LOCUS       sequence-10711-e        3258 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 3258)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 3258)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-BUB1
FEATURES             Location/Qualifiers
     source          1..3258
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 atggacaccc cggaaaatgt ccttcagatg cttgaagccc acatgcagag ctacaagggc
       61 aatgaccctc ttggtgaatg ggaaagatac atacagtggg tagaagagaa ttttcctgag
      121 aataaagaat acttgataac tttactagaa catttaatga aggaattttt agataagaag
      181 aaataccaca atgacccaag attcatcagt tattgtttaa aatttgctga gtacaacagt
      241 gacctccatc aattttttga gtttctgtac aaccatggga ttggaaccct gtcatcccct
      301 ctgtacattg cctgggcggg gcatctggaa gcccaaggag agctgcagca tgccagtgct
      361 gtccttcaga gaggaattca aaaccaggct gaacccagag agttcctgca acaacaatac
      421 aggttatttc agacacgcct cactgaaacc catttgccag ctcaagctag aacctcagaa
      481 cctctgcata atgttcaggt tttaaatcaa atgataacat caaaatcaaa tccaggaaat
      541 aacatggcct gcatttctaa gaatcagggt tcagagcttt ctggagtgat atcttcagct
      601 tgtgataaag agtcaaatat ggaacgaaga gtgatcacga tttctaaatc agaatattct
      661 gtgcactcat ctttggcatc caaagttgat gttgagcagg ttgttatgta ttgcaaggag
      721 aagcttattc gtggggaatc agaattttcc tttgaagaat tgagagccca gaaatacaat
      781 caacggagaa agcatgagca atgggtaaat gaagacagac attatatgaa aaggaaagaa
      841 gcaaatgctt ttgaagaaca gctattaaaa cagaaaatgg atgaacttca taagaagttg
      901 catcaggtgg tggagacatc ccatgaggat ctgcccgctt cccaggaaag gtccgaggtt
      961 aatccagcac gtatggggcc aagtgtaggc tcccagcagg aactgagagc gccatgtctt
     1021 ccagtaacct atcagcagac accagtgaac atggaaaaga acccaagaga ggcacctcct
     1081 gttgttcctc ctttggcaaa tgctatttct gcagctttgg tgtccccagc caccagccag
     1141 agcattgctc ctcctgttcc tttgaaagcc cagacagtaa cagactccat gtttgcagtg
     1201 gccagcaaag atgctggatg tgtgaataag agtactcatg aattcaagcc acagagtgga
     1261 gcagagatca aagaagggtg tgaaacacat aaggttgcca acacaagttc ttttcacaca
     1321 actccaaaca catcactggg aatggttcag gcaacgccat ccaaagtgca gccatcaccc
     1381 accgtgcaca caaaagaagc attaggtttc atcatgaata tgtttcaggc tcctacactt
     1441 cctgatattt ctgatgacaa agatgaatgg caatctctag atcaaaatga agatgcattt
     1501 gaagcccagt ttcaaaaaaa tgtaaggtca tctggggctt ggggagtcaa taagatcatc
     1561 tcttctttgt catctgcttt tcatgtgttt gaagatggaa acaaagaaaa ttatggatta
     1621 ccacagccta aaaataaacc cacaggagcc aggacctttg gagaacgctc tgtcagcaga
     1681 cttccttcaa aaccaaagga ggaagtgcct catgctgaag agtttttgga tgactcaact
     1741 gtatggggta ttcgctgcaa caaaaccctg gcacccagtc ctaagagccc aggagacttc
     1801 acatctgctg cacaacttgc gtctacacca ttccacaagc ttccagtgga gtcagtgcac
     1861 attttagaag ataaagaaaa tgtggtagca aaacagtgta cccaggcgac tttggattct
     1921 tgtgaggaaa acatggtggt gccttcaagg gatggaaaat tcagtccaat tcaagagaaa
     1981 agcccaaaac aggccttgtc gtctcacatg tattcagcat ccttacttcg tctgagccag
     2041 cctgctgcag gtggggtact tacctgtgag gcagagttgg gcgttgaggc ttgcagactc
     2101 acagacactg acgctgccat tgcagaagat ccaccagatg ctattgctgg gctccaagca
     2161 gaatggatgc agatgagttc acttgggact gttgatgctc caaacttcat tgttgggaac
     2221 ccatgggatg ataagctgat tttcaaactt ttatctgggc tttctaaacc agtgagttcc
     2281 tatccaaata cttttgaatg gcaatgtaaa cttccagcca tcaagcccaa gactgaattt
     2341 caattgggtt ctaagctggt ctatgtccat caccttcttg gagaaggagc ctttgcccag
     2401 gtgtacgaag ctacccaggg agatctgaat gatgctaaaa ataaacagaa atttgtttta
     2461 aaggtccaaa agcctgccaa cccctgggaa ttctacattg ggacccagtt gatggaaaga
     2521 ctaaagccat ctatgcagca catgtttatg aagttctatt ctgcccactt attccagaat
     2581 ggcagtgtat tagtaggaga gctctacagc tatggaacat tattaaatgc cattaacctc
     2641 tataaaaata cccctgaaaa agtgatgcct caaggtcttg tcatctcttt tgctatgaga
     2701 atgctttaca tgattgagca agtgcatgac tgtgaaatca ttcatggaga cattaaacca
     2761 gacaatttca tacttggaaa cggatttttg gaacaggatg atgaagatga tttatctgct
     2821 ggcttggcac tgattgacct gggtcagagt atagatatga aactttttcc aaaaggaact
     2881 atattcacag caaagtgtga aacatctggt tttcagtgtg ttgagatgct cagcaacaaa
     2941 ccatggaact accagatcga ttactttggg gttgctgcaa cagtatattg catgctcttt
     3001 ggcacttaca tgaaagtgaa aaatgaagga ggagagtgta agcctgaagg tctttttaga
     3061 aggcttcctc atttggatat gtggaatgaa ttttttcatg ttatgttgaa tattccagat
     3121 tgtcatcatc ttccatcttt ggatttgtta aggcaaaagc tgaagaaagt atttcaacaa
     3181 cactatacta acaagattag ggccctacgt aataggctaa ttgtactgct cttagaatgt
     3241 aagcgttcac gaaaataa
//
