LOCUS       sequence-107125-         682 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  Expression of human RNF168 ring domain (residues 1-189) tagged with 
            His-SUMO.
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 682)
  AUTHORS   Mattiroli F, Vissers JH, van Dijk WJ, Ikpa P, Citterio E, Vermeulen 
            W, Marteijn JA, Sixma TK
  TITLE     RNF168 ubiquitinates K13-15 on H2A/H2AX to drive DNA damage 
            signaling.
  JOURNAL   Cell. 2012 Sep 14;150(6):1182-95. doi: 10.1016/j.cell.2012.08.005.
  PUBMED    22980979
REFERENCE   2  (bases 1 to 682)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: 
            "10.1016/j.cell.2012.08"; journalName: "Cell"; date: "2012-09-14- 
            14"; volume: "150"; issue: "6"; pages: "1182-95"
COMMENT     Sequence Label: pETNKI-his-SUMO-RNF168ring (1-189)
FEATURES             Location/Qualifiers
     source          1..682
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     CDS             18..35
                     /codon_start=1
                     /product="6xHis affinity tag"
                     /label=6xHis
                     /translation="HHHHHH"
     CDS             42..317
                     /codon_start=1
                     /product="human small ubiquitin-related modifier 3"
                     /label=SUMO3
                     /translation="MSEEKPKEGVKTENDHINLKVAGQDGSVVQFKIKRHTPLSKLMKA
                     YCERQGLSMRQIRFRFDGQPINETDTPAQLEMEDEDTIDVFQQQTGG"
ORIGIN
        1 ggagatatac catgggtcat caccatcatc atcacggagg tatgtccgag gagaagccca
       61 aggagggtgt gaagacagag aatgaccaca tcaacctgaa ggtggccggg caggacggct
      121 ccgtggtgca gttcaagatc aagaggcaca cgccgctgag caagctgatg aaggcctact
      181 gcgagaggca gggcttgtca atgaggcaga tcagattcag gttcgacggg cagccaatca
      241 atgaaactga cactccagca cagctggaga tggaggacga ggacaccatc gacgtgttcc
      301 agcagcagac gggaggtatg gctctaccca aagacgccat cccctcgctg tccgagtgcc
      361 agtgcgggat ctgcatggaa atcctcgtgg agcccgtcac cctcccgtgt aaccacacgc
      421 tgtgtaaacc gtgcttccag tcgaccgtcg aaaaggcgag tttatgctgt cccttctgtc
      481 gccgccgggt atcgtcgtgg actcggtacc atacccgaag aaattctctc gtcaacgtgg
      541 aactgtggac gataattcaa aaacactatc ccagggagtg caagcttaga gcgtctggcc
      601 aagaatcaga ggaagtggct gatgactatc agccagttcg tctgctcagt aaacctgggg
      661 aactgagaag agaatatgaa ga
//
