LOCUS       sequence-10713-e        2493 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 2493)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 2493)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-MGC16169
FEATURES             Location/Qualifiers
     source          1..2493
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 atgtttcccc tgaaggacgc tgaaatggga gcctttacct tctttgcctc ggctctgcca
       61 catgatgttt gtggaagcaa tggacttcct ctcacaccaa attccatcaa aattttaggg
      121 cgctttcaaa tccttaaaac catcacccat cccagactct gccagtatgt ggatatttct
      181 aggggaaagc atgaacgact agtggtcgtg gctgaacatt gtgaacgtag tctggaagac
      241 ttgcttcgag aaaggaaacc tgtgaggtat ccctcgtact tggcccctga ggtaattgca
      301 cagggaattt tcaaaaccac tgatcacatg ccaagtaaaa aaccattgcc ttctggcccc
      361 aaatcagatg tatggtctct tggaatcatt ttatttgagc tttgtgtggg aagaaaatta
      421 tttcagagct tggatatttc tgaaagacta aaatttttgc ttactttgga ttgtgtagat
      481 gacactttaa tagttctggc tgaagagcat ggttgtttgg acattataaa ggagcttcct
      541 gaaactgtga tagatctttt gaataagtgc cttaccttcc atccttctaa gaggccaacc
      601 ccagatgaat taatgaagga caaagtattc agtgaggtat cacctttata tacccccttt
      661 accaaacctg ccagtctgtt ttcatcttct ctgagatgtg ctgatttaac tctgcctgag
      721 gatatcagtc agttgtgtaa agatataaat aatgattacc tggcagaaag atctattgaa
      781 gaagtgtatt acctttggtg tttggctgga ggtgacttgg agaaagagct tgtcaacaag
      841 gaaatcattc gatccaaacc acctatctgc acactcccca attttctctt tgaggatggt
      901 gaaagctttg gacaaggtcg agatagaagc tcgcttttag atgataccac tgtgacattg
      961 tcgttatgcc agctaagaaa tagattgaaa gatgttggtg gagaagcatt ttacccatta
     1021 cttgaagatg accagtctaa tttacctcat tcaaacagca ataatgagtt gtctgcagct
     1081 gccacgctcc ctttaatcat cagagagaag gatacagagt accaactaaa tagaattatt
     1141 ctcttcgaca ggctgctaaa ggcttatcca tataaaaaaa accaaatctg gaaagaagca
     1201 agagttgaca ttcctcctct tatgagaggt ttaacctggg ctgctcttct gggagttgag
     1261 ggagctattc atgccaagta cgatgcaatt gataaagaca ctccaattcc tacagataga
     1321 caaattgaag tggatattcc tcgctgtcat cagtacgatg aactgttatc atcaccagaa
     1381 ggtcatgcaa aatttaggcg tgtattaaaa gcctgggtag tgtctcatcc tgatcttgtg
     1441 tattggcaag gtcttgactc actttgtgct ccattcctat atctaaactt caataatgaa
     1501 gccttggctt atgcatgtat gtctgctttt attcccaaat acctgtataa cttcttctta
     1561 aaagacaact cacatgtaat acaagagtat ctgactgtct tctctcagat gattgcattt
     1621 catgatccag agctgagtaa tcatctcaat gagattggtt tcattccaga tctctatgcc
     1681 atcccttggt ttcttaccat gtttactcat gtatttccac tacacaaaat tttccacctc
     1741 tgggatacct tactacttgg gaattcctct ttcccattct gtattggagt agcaattctt
     1801 cagcagctgc gggaccggct tttggctaat ggctttaatg agtgtattct tctcttctcc
     1861 gatttaccag aaattgacat tgaacgctgt gtgagagaat ctatcaacct gttttgttgg
     1921 actcctaaaa gtgctactta cagacagcat gctcaacctc caaagccatc ttctgacagc
     1981 agtggaggca gaagttcggc accttatttc tctgctgagt gtccagatcc tccaaagaca
     2041 gatctgtcaa gagaatccat cccattaaat gacctgaagt cagaagtatc accacggatt
     2101 tcagcagagg acctgattga cttgtgtgag ctcacagtga caggccactt caaaacaccc
     2161 agcaagaaaa caaagtccag taaaccaaag ctcctggtgg ttgacatccg gaatagtgaa
     2221 gactttattc gtggtcacat ttcaggaagc atcaacattc cattcagtgc tgccttcact
     2281 gcagaagggg agcttaccca gggcccttac actgctatgc tccagaactt caaagggaag
     2341 gtcattgtca tcgtggggca tgtggcaaaa cacacagctg agtttgcagc tcaccttgtg
     2401 aagatgaaat atccaagaat ctgtattcta gatggtggca ttaataaaat aaagccaaca
     2461 ggcctcctca ccatcccatc tcctcaaata tga
//
