LOCUS       sequence-10730-e        1296 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 1296)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 1296)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-STK24
FEATURES             Location/Qualifiers
     source          1..1296
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     regulatory      1226..1235
                     /label=Kozak sequence
                     /note="vertebrate consensus sequence for strong initiation 
                     of translation (Kozak, 1987)"
                     /regulatory_class="other"
ORIGIN
        1 atggctcact ccccggtgca gtcgggcctg cccggcatgc agaacctaaa ggcagaccca
       61 gaagagcttt ttacaaaact agagaaaatt gggaagggct cctttggaga ggtgttcaaa
      121 ggcattgaca atcggactca gaaagtggtt gccataaaga tcattgatct ggaagaagct
      181 gaagatgaga tagaggacat tcaacaagaa atcacagtgc tgagtcagtg tgacagtcca
      241 tatgtaacca aatattatgg atcctatctg aaggatacaa aattatggat aataatggaa
      301 tatcttggtg gaggctccgc actagatcta ttagaacctg gcccattaga tgaaacccag
      361 atcgctacta tattaagaga aatactgaaa ggactcgatt atctccattc ggagaagaaa
      421 atccacagag acattaaagc ggccaacgtc ctgctgtctg agcatggcga ggtgaagctg
      481 gcggactttg gcgtggctgg ccagctgaca gacacccaga tcaaaaggaa caccttcgtg
      541 ggcaccccat tctggatggc acccgaggtc atcaaacagt cggcctatga ctcgaaggca
      601 gacatctggt ccctgggcat aacagctatt gaacttgcaa gaggggaacc acctcattcc
      661 gagctgcacc ccatgaaagt tttattcctc attccaaaga acaacccacc gacgttggaa
      721 ggaaactaca gtaaacccct caaggagttt gtggaggcct gtttgaataa ggagccgagc
      781 tttagaccca ctgctaagga gttattgaag cacaagttta tactacgcaa tgcaaagaaa
      841 acttcctact tgaccgagct catcgacagg tacaagagat ggaaggccga gcagagccat
      901 gacgactcga gctccgagga ttccgacgcg gaaacagatg gccaagcctc ggggggcagt
      961 gattctgggg actggatctt cacaatccga gaaaaagatc ccaagaatct cgagaatgga
     1021 gctcttcagc catcggactt ggacagaaat aagatgaaag acatcccaaa gaggcctttc
     1081 tctcagtgtt tatctacaat tatttctcct ctgtttgcag agttgaagga gaagagccag
     1141 gcgtgcggag ggaacttggg gtccattgaa gagctgcgag gggccatcta cctagcggag
     1201 gaggcgtgcc ctggcatctc cgacaccatg gtggcccagc tcgtgcagcg gctccagaga
     1261 tactctctaa gtggtggagg aacttcatcc cactga
//
