LOCUS       sequence-10743-e        1968 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 1968)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 1968)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-SRPK1
FEATURES             Location/Qualifiers
     source          1..1968
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 atggagcgga aagtgcttgc gctccaggcc cgaaagaaaa ggaccaaggc caagaaggac
       61 aaagcccaaa ggaaatctga aactcagcac cgaggctctg ctccccactc tgagagtgat
      121 ctaccagagc aggaagagga gattctggga tctgatgatg atgagcaaga agatcctaat
      181 gattattgta aaggaggtta tcatcttgtg aaaattggag atctattcaa tgggagatac
      241 catgtgatcc gaaagttagg ctggggacac ttttcaacag tatggttatc atgggatatt
      301 caggggaaga aatttgtggc aatgaaagta gttaaaagtg ctgaacatta cactgaaaca
      361 gcactagatg aaatccggtt gctgaagtca gttcgcaatt cagaccctaa tgatccaaat
      421 agagaaatgg ttgttcaact actagatgac tttaaaatat caggagttaa tggaacacat
      481 atctgcatgg tatttgaagt tttggggcat catctgctca agtggatcat caaatccaat
      541 tatcaggggc ttccactgcc ttgtgtcaaa aaaattattc agcaagtgtt acagggtctt
      601 gattatttac ataccaagtg ccgtatcacc cacactgaca ttaaaccaga gaacatctta
      661 ttgtcagtga atgagcagta cattcggagg ctggctgcag aagcaacaga atggcagcga
      721 tctggagctc ctccgccttc cggatctgca gtcagtactg ctccccagcc taaaccagct
      781 gacaaaatgt caaagaataa gaagaagaaa ttgaagaaga agcagaagcg ccaggcagaa
      841 ttactagaga agcgaatgca ggaaattgag gaaatggaga aagagtcggg ccctgggcaa
      901 aaaagaccaa acaagcaaga agaatcagag agtcctgttg aaagaccctt gaaagagaac
      961 ccacctaata aaatgaccca agaaaaactt gaagagtcaa gtaccattgg ccaggatcaa
     1021 acgcttatgg aacgtgatac agagggtggt gcagcagaaa ttaattgcaa tggagtgatt
     1081 gaagtcatta attatactca gaacagtaat aatgaaacat tgagacataa agaggatcta
     1141 cataatgcta atgactgtga tgtccaaaat ttgaatcagg aatctagttt cctaagctcc
     1201 caaaatggag acagcagcac atctcaagaa acagactctt gtacacctat aacatctgag
     1261 gtgtcagaca ccatggtgtg ccagtcttcc tcaactgtag gtcagtcatt cagtgaacaa
     1321 cacattagcc aacttcaaga aagcattcgg gcagagatac cctgtgaaga tgaacaagag
     1381 caagaacata acggaccact ggacaacaaa ggaaaatcca cggctggaaa ttttcttgtt
     1441 aatccccttg agccaaaaaa tgcagaaaag ctcaaggtga agattgctga ccttggaaat
     1501 gcttgttggg tgcacaaaca tttcactgaa gatattcaaa caaggcaata tcgttccttg
     1561 gaagttctaa tcggatctgg ctataatacc cctgctgaca tttggagcac ggcatgcatg
     1621 gcctttgaac tggccacagg tgactatttg tttgaacctc attcagggga agagtacact
     1681 cgagatgaag atcacattgc attgatcata gaacttctgg ggaaggtgcc tcgcaagctc
     1741 attgtggcag gaaaatattc caaggaattt ttcaccaaaa aaggtgacct gaaacatatc
     1801 acgaagctga aaccttgggg cctttttgag gttctagtgg agaagtatga gtggtcgcag
     1861 gaagaggcag ctggcttcac agatttctta ctgcccatgt tggagctgat ccctgagaag
     1921 agagccactg ccgccgagtg tctccggcac ccttggctta actcctaa
//
