LOCUS       sequence-10744-e        1845 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 1845)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 1845)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-PAPSS2
FEATURES             Location/Qualifiers
     source          1..1845
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 atgtcgggga tcaagaagca aaagacggag aaccagcaga aatccaccaa tgtagtctat
       61 caggcccacc atgtgagcag gaataagaga gggcaagtgg ttggaacaag gggtgggttc
      121 cgaggatgta ccgtgtggct aacaggtctc tctggtgctg gaaaaacaac gataagtttt
      181 gccctggagg agtaccttgt ctcccatgcc atcccttgtt actccctgga tggggacaat
      241 gtccgtcatg gccttaacag aaatctcgga ttctctcctg gggacagaga ggaaaatatc
      301 cgccggattg ctgaggtggc taagctgttt gctgatgctg gtctggtctg cattaccagc
      361 tttatttctc cattcgcaaa ggatcgtgag aatgcccgca aaatacatga atcagcaggg
      421 ctgccattct ttgaaatatt tgtagatgca cctctaaata tttgtgaaag cagagacgta
      481 aaaggcctct ataaaagggc cagagctggg gagattaaag gatttacagg tattgattct
      541 gattatgaga aacctgaaac tcctgagcgt gtgcttaaaa ccaatttgtc cacagtgagt
      601 gactgtgtcc accaggtagt ggaacttctg caagagcaga acattgtacc ctatactata
      661 atcaaagata tccacgaact ctttgtgccg gaaaacaaac ttgaccacgt ccgagctgag
      721 gctgaaactc tcccttcatt atcaattact aagctggatc tccagtgggt ccaggttttg
      781 agcgaaggct gggccactcc cctcaaaggt ttcatgcggg agaaggagta cttacaggtt
      841 atgcactttg acaccctgct agatgatggc gtgatcaaca tgagcatccc cattgtactg
      901 cccgtctctg cagaggataa gacacggctg gaagggtgca gcaagtttgt cctggcacat
      961 ggtggacgga gggtagctat cttacgagac gctgaattct atgaacacag aaaagaggaa
     1021 cgctgttccc gtgtttgggg gacaacatgt acaaaacacc cccatatcaa aatggtgatg
     1081 gaaagtgggg actggctggt tggtggagac cttcaggtgc tggagaaaat aagatggaat
     1141 gatgggctgg accaataccg tctgacacct ctggagctca aacagaaatg taaagaaatg
     1201 aatgctgatg cggtgtttgc attccagttg cgcaatcctg tccacaatgg ccatgccctg
     1261 ttgatgcagg acactcgccg caggctccta gagaggggct acaagcaccc ggtcctccta
     1321 ctacaccctc tgggcggctg gaccaaggat gacgatgtgc ctctagactg gcggatgaag
     1381 cagcacgcgg ctgtgctcga ggaaggggtc ctggatccca agtcaaccat tgttgccatc
     1441 tttccgtctc ccatgttata tgctggcccc acagaggtcc agtggcactg caggtcccgg
     1501 atgattgcgg gtgccaattt ctacattgtg gggagggacc ctgcaggaat gccccatcct
     1561 gaaaccaaga aggatctgta tgaacccact catgggggca aggtcttgag catggcccct
     1621 ggcctcacct ctgtggaaat cattccattc cgagtggctg cctacaacaa agccaaaaaa
     1681 gccatggact tctatgatcc agcaaggcac aatgagtttg acttcatctc aggaactcga
     1741 atgaggaagc tcgcccggga aggagagaat cccccagatg gcttcatggc ccccaaagca
     1801 tggaaggtcc tgacagatta ttacaggtcc ctggagaaga actaa
//
