LOCUS       sequence-10746-e        1278 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 1278)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 1278)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-SH3BP5
FEATURES             Location/Qualifiers
     source          1..1278
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     regulatory      475..484
                     /label=Kozak sequence
                     /note="vertebrate consensus sequence for strong initiation 
                     of translation (Kozak, 1987)"
                     /regulatory_class="other"
ORIGIN
        1 atggagcagg ggctggagga ggaagaagag gtggatcccc ggatccaggg agaactggag
       61 aagttaaatc agtccacgga tgatatcaac agacgggaga ctgaacttga ggatgctcgt
      121 cagaagttcc gctctgttct ggttgaagca acggtgaaac tggatgaact ggtgaagaaa
      181 attggcaaag ctgtggaaga ctccaagccc tactgggagg cacggagggt ggcgaggcag
      241 gctcagctgg aagctcagaa agccacgcag gacttccaga gggccacaga ggtgctccgt
      301 gccgccaagg agaccatctc cctggccgag cagcggctgc tggaggatga caagcggcag
      361 ttcgactccg cctggcagga gatgctgaat cacgccactc agagggtcat ggaggcggag
      421 cagaccaaga ccaggagcga gctggtgcat aaggagacgg cagccaggta caatgccgcc
      481 atgggccgca tgcgacagct ggagaagaaa ctcaagagag ccatcaacaa gtccaagcct
      541 tattttgaac tcaaggcaaa gtactatgtg cagctcgagc aactgaaaaa gactgtggat
      601 gacctgcagg ccaaactgac cctggcaaaa ggcgagtaca agatggccct gaagaacctg
      661 gagatgatct cagatgagat ccacgagcgg cggcgctcca gtgccatggg gcctcgggga
      721 tgcggtgttg gtgctgaggg cagcagcaca tctgtggagg atctgccagg gagcaaacct
      781 gagcctgatg ccatttctgt ggcctcggag gcctttgaag atgacagctg tagcaacttt
      841 gtgtctgaag atgactcgga aacccagtcc gtgtccagct ttagttcagg accaacaagc
      901 ccgtctgaga tgcctgacca gttccctgcg gttgtgaggc ctggcagcct ggatctgccc
      961 agccctgtgt ccctgtcaga gtttgggatg atgttcccag tgttgggccc tcgaagtgaa
     1021 tgcagcgggg cctcctcccc tgaatgtgaa gtagaacgag gagacagggc agaaggggca
     1081 gagaataaaa caagtgacaa agccaacaac aaccggggcc tcagcagtag cagtggcagt
     1141 ggtggcagca gtaagagcca aagcagcacc tcccctgagg gccaggcctt ggagaaccgg
     1201 atgaagcagc tctccctaca gtgctcaaag ggaagagatg gaattattgc tgacataaaa
     1261 atggtgcaga ttggctga
//
