LOCUS       sequence-10748-e        1236 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 1236)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 1236)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-PDK4
FEATURES             Location/Qualifiers
     source          1..1236
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 atgaaggcgg cccgcttcgt gctgcgcagc gctggctcgc tcaacggcgc cggcctggtg
       61 ccccgagagg tggagcattt ctcgcgctac agcccgtccc cgctgtccat gaagcagcta
      121 ctggactttg gttcagaaaa tgcatgtgaa agaacttctt ttgcattttt gcgacaagaa
      181 ttgcctgtga gactcgccaa cattctgaag gaaattgata tcctcccgac ccaattagta
      241 aatacctctt cagtgcaatt ggttaaaagc tggtatatac agagcctgat ggatttggtg
      301 gaattccatg agaaaagccc agatgaccag aaagcattat cagactttgt agatacactc
      361 atcaaagttc gaaatagaca ccataatgta gtccctacaa tggcacaagg aatcatagag
      421 tataaagatg cctgtacagt tgacccagtc accaatcaaa atcttcaata tttcttggat
      481 cgattttaca tgaaccgtat ttctactcgg atgctgatga accagcacat tcttatattt
      541 agtgactcac agacaggaaa cccaagccac attggaagca ttgatcctaa ctgtgatgtg
      601 gtagcagtgg tccaagatgc ctttgagtgt tcaaggatgc tctgtgatca gtattattta
      661 tcatctccag aattaaagct tacacaagtg aatggaaaat ttccagacca accaattcac
      721 atcgtgtatg ttccttctca cctccatcat atgctctttg aactatttaa gaatgcaatg
      781 cgggcaacag ttgaacacca ggaaaatcag ccttccctta caccaataga ggttattgtt
      841 gtcttgggaa aagaagacct taccattaag atttcagaca gaggaggtgg tgttcccctg
      901 agaattattg accgcctctt tagttataca tactccactg caccaacgcc tgtgatggat
      961 aattcccgga atgctccttt ggctggtttt ggttacggct tgccaatttc tcgtctgtat
     1021 gccaagtact ttcaaggaga tctgaatctc tactctttat caggatatgg aacagatgct
     1081 atcatctact taaaggcttt gtcttctgag tctatagaaa aacttccagt ttttaacaag
     1141 tcagccttca aacattatca gatgagctct gaggctgatg actggtgtat cccaagcagg
     1201 gaaccaaaga acctggcaaa agaagtggcc atgtga
//
