LOCUS       sequence-10750-e         585 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 585)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 585)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-AK1
FEATURES             Location/Qualifiers
     source          1..585
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     regulatory      236..245
                     /label=Kozak sequence
                     /note="vertebrate consensus sequence for strong initiation 
                     of translation (Kozak, 1987)"
                     /regulatory_class="other"
ORIGIN
        1 atggaagaga agctgaagaa aaccaatatc atctttgtgg tgggtgggcc tggctcaggg
       61 aagggcaccc agtgtgagaa gatcgtgcag aagtatggct acacccacct ctccaccggg
      121 gacctcctgc ggtccgaggt cagctcaggc tcggccaggg gcaagaagct gtcggaaatc
      181 atggagaagg ggcagctggt tccactggag acagtgttgg acatgctccg ggatgccatg
      241 gtggccaaag tcaatacttc caaaggcttc ctgattgatg gctacccgcg ggaggtgcag
      301 caaggagaag agtttgagcg acggattgga cagcccacac tgctgctgta tgtggacgca
      361 ggccctgaga ccatgaccca gcggctcttg aaacgtggag agaccagcgg gcgtgtggac
      421 gacaatgagg agaccatcaa aaagcggctg gagacctatt acaaggccac agaacccgtc
      481 atcgccttct atgagaaacg tggcattgtg cgcaaggtca acgctgaggg ctccgtggac
      541 agtgtcttct cccaggtctg cacccacctg gacgccctaa agtag
//
