LOCUS       sequence-10757-e        1608 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 1608)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 1608)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-NRBP
FEATURES             Location/Qualifiers
     source          1..1608
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 atgtcggagg gggagtccca gacagtactt agcagtggct cagacccaaa ggtagaatcc
       61 tcatcttcag ctcctggcct gacatcagtg tcacctcctg tgacctccac aacctcagct
      121 gcttccccag aggaagaaga agaaagtgaa gatgagtctg agattttgga agagtcgccc
      181 tgtgggcgct ggcagaagag gcgagaagag gtgaatcaac ggaatgtacc aggtattgac
      241 agtgcatacc tggccatgga tacagaggaa ggtgtagagg ttgtgtggaa tgaggtacag
      301 ttctctgaac gcaagaacta caagctgcag gaggaaaagg ttcgtgctgt gtttgataat
      361 ctgattcaat tggagcatct taacattgtt aagtttcaca aatattgggc tgacattaaa
      421 gagaacaagg ccagggtcat ttttatcaca gaatacatgt catctgggag tctgaagcaa
      481 tttctgaaga agaccaaaaa gaaccacaag acgatgaatg aaaaggcatg gaagcgttgg
      541 tgcacacaaa tcctctctgc cctaagctac ctgcactcct gtgacccccc catcatccat
      601 gggaacctga cctgtgacac catcttcatc cagcacaacg gactcatcaa gattggctct
      661 gtggctcctg acactatcaa caatcatgtg aagacttgtc gagaagagca gaagaatcta
      721 cacttctttg caccagagta tggagaagtc actaatgtga caacagcagt ggacatctac
      781 tcctttggca tgtgtgcact ggagatggca gtgctggaga ttcagggcaa tggagagtcc
      841 tcatatgtgc cacaggaagc catcagcagt gccatccagc ttctagaaga cccattacag
      901 agggagttca ttcaaaagtg cctgcagtct gagcctgctc gcagaccaac agccagagaa
      961 cttctgttcc acccagcatt gtttgaagtg ccctcgctca aactccttgc ggcccactgc
     1021 attgtgggac accaacacat gatcccagag aacgctctag aggagatcac caaaaacatg
     1081 gatactagtg ccgtactggc tgaaatccct gcaggaccag gaagagaacc agttcagact
     1141 ttgtactctc agtcaccagc tctggaatta gataaattcc ttgaagatgt caggaatggg
     1201 atctatcctc tgacagcctt tgggctgcct cggccccagc agccacagca ggaggaggtg
     1261 acatcacctg tcgtgccccc ctctgtcaag actccgacac ctgaaccagc tgaggtggag
     1321 actcgcaagg tggtgctgat gcagtgcaac attgagtcgg tggaggaggg agtcaaacac
     1381 cacctgacac ttctgctgaa gttggaggac aaactgaacc ggcacctgag ctgtgacctg
     1441 atgccaaatg agaatatccc cgagttggcg gctgagctgg tgcagctggg cttcattagt
     1501 gaggctgacc agagccggtt gacttctctg ctagaagaga ccttgaacaa gttcaatttt
     1561 gccaggaaca gtaccctcaa ctcagccgct gtcaccgtct cctcttag
//
