LOCUS       sequence-10775-e         850 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 850)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 850)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-PRKCA
FEATURES             Location/Qualifiers
     source          1..850
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     protein_bind    4..103
                     /gene="mutant version of attL"
                     /label=attL1
                     /bound_moiety="LR Clonase(TM)"
                     /note="recombination site for the Gateway(R) LR reaction"
ORIGIN
        1 cccaaataaa tgattttatt ttgactgata gtgacctgtt cgttgcaaca aattgatgag
       61 caatgctttt ttataatgcc aactttgtac aaaaaagttg gcaccatggc tgacgttttc
      121 ccgggcaacg actccacggc gtctcaggac gtggccaacc gcttcgcccg caaaggggcg
      181 ctgaggcaga agaacgtgca cgaggtgaag gaccacaaat tcatcgcgcg cttcttcaag
      241 cagcccacct tctgcagcca ctgcaccgac ttcatctggg ggtttgggaa acaaggcttc
      301 cagtgccaag tttgctgttt tgtggtccac aagaggtgcc atgaatttgt tactttttct
      361 tgtccgggtg cggataaggg acccgacact gatgacccca ggagcaagca caagttcaaa
      421 atccacactt acggaagccc caccttctgc gatcactgtg ggtcactgct ctatggactt
      481 atccatcaag ggatgaaatg tgacacctgc gatatgaacg ttcacaagca atgcgtcatc
      541 aatgtcccca gcctctgcgg aatggatcac actgagaaga gggggcggat ttacctaaag
      601 gctgaggttg ctgatgaaaa gctccatgtc acagtacgag atgcaaaaaa tctaatccct
      661 atggatccaa acgggctttc agatccttat gtgaagctga aacttattcc tgatcccaag
      721 aatgaaagca agcaaaaaac caaaaccatc cgctccacac taaatccgca gtgaaatgaa
      781 tcctttactt tcaatttgaa acctttcgac aaagaccgac aactgtctgt agaaatctgg
      841 gactgggaac
//
