LOCUS       sequence-10776-e         873 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 873)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 873)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-PRKAG3
FEATURES             Location/Qualifiers
     source          1..873
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     protein_bind    102..126
                     /gene="mutant version of attB"
                     /label=attB1
                     /bound_moiety="BP Clonase(TM)"
                     /note="recombination site for the Gateway(R) BP reaction"
ORIGIN
        1 ggggggnggg gggcgtgaat agctgggccc aatatgattt tattttgact gatagtgacc
       61 tgttcgttgc acaaattgat gagcaatgct tttttataat gccaactttg tacaaaaaag
      121 ttggcaccat ggagcccggg ctggagcacg cactgcgcag gaccccttcc tggagcagcc
      181 ttgggggttc tgagcatcaa gagatgagct tcctagagca agaaaacagc agctcatggc
      241 catcaccagc tgtgaccagc agctcagaaa gaatccgtgg gaaacggagg gccaaagcct
      301 tgagatggac aaggcagaag tcggtggagg aaggggagcc accaggtcag ggggaaggtc
      361 cccggtccag gccagctgct gagtccaccg ggctggaggc cacattcccc aagaccacac
      421 ccttggctca agctgatcct gccggggtgg gcactccacc aacagggtgg gactgcctcc
      481 cctctgactg tacagcctca gctgcaggct ccagcacaga tgatgtggag ctggccacgg
      541 agttcccagc cacagaggcc tgggagtgtg agctagaagg cctgctggaa gagaggcctg
      601 ccctgtgcct gtccccgcag gccccatttc ccaagctggg ctgggatgac gaactgcgga
      661 aacccggcgc ccagatctac atgcgcttca tgcaggagca cacctgctac gatgccatgg
      721 caactagctc caagctagtc atcttcgaca ccatgctgga gatcaagaag gccttctttg
      781 ctctggtggc caacggggtg cgggcagccc ctctatggga cagcaagaag cagagctttt
      841 gtggggatgc tgaccatcac tgactttttc ctg
//
