LOCUS       sequence-10784-e         941 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 941)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 941)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-PIK4CA
FEATURES             Location/Qualifiers
     source          1..941
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     protein_bind    71..95
                     /gene="mutant version of attB"
                     /label=attB1
                     /bound_moiety="BP Clonase(TM)"
                     /note="recombination site for the Gateway(R) BP reaction"
ORIGIN
        1 aatgatttta ttttgactga tagtgacctg ttcgttgcaa caaattgatg agcaatgctt
       61 ttttataatg ccaactttgt acaaaaaagt tggcatgcgg gagatggcag gggcctggca
      121 catgacggtg gagcagaaat ttggcctgtt ttctgctgag ataaaggaag cagaccccct
      181 ggctgcctcg gaagcaagtc aacccaaacc ctgtcccccc gaagtgaccc cccactacat
      241 ctggatcgac ttcctggtgc agcggtttga gatcgccaag tactgcagct ctgaccaagt
      301 ggagatcttc tccagcctgc tgcagcgctc catgtccctg aacatcggcg gggccaaggg
      361 gagcatgaac cggcacgtgg cggccatcgg gccccgcttc aagctgctga ccctggggct
      421 gtccctcctg catgccgatg tggttccaaa tgcaaccatc cgcaatgtgc ttcgcgagaa
      481 gatctactcc actgcctttg actacttcag ctgtccccca aagttcccta ctcaaggaga
      541 gaagcggctg cgtgaagaca taagcatcat gattaaattt tggaccgcca tgttctcaga
      601 taagaagtac ctgaccgcca gccagcttgt tcccccagat aatcaggaca cccggagcaa
      661 cctggacata actgtcggct ctcggcaaca agccacccaa ggctggatca acacataccc
      721 cctgtccagc ggcatgtcca ccatctccaa gaaatcagca tgtctaagaa aaccaaccgg
      781 ggctcccagc tgcacaaata ctacatgaag cgcagacgct gctgctgtcc ctgctggcca
      841 ctgagatcga gcgtctcatc acatggtaca cccgctgtca gccccggaac tggaactaga
      901 caaggccgaa aaagaacagc cgtggccact gggagattct a
//
