LOCUS       sequence-10836-e         874 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 874)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 874)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-MAP4K4
FEATURES             Location/Qualifiers
     source          1..874
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     protein_bind    65..89
                     /gene="mutant version of attB"
                     /label=attB1
                     /bound_moiety="BP Clonase(TM)"
                     /note="recombination site for the Gateway(R) BP reaction"
ORIGIN
        1 attattttga ctgatagtga cctgttcgtt gcaacaaatt gatgagcaat gcttttttat
       61 aatgccaact ttgtacaaaa aagttggcac catggcgaac gactcccctg caaaaagtct
      121 ggtggacatc gacctctcct ccctgcggga tcctgctggg atttttgagc tggtggaagt
      181 ggttggaaat ggcacctatg gacaagtcta taagggtcga catgttaaaa cgggtcagtt
      241 ggcagccatc aaagttatgg atgtcactga ggatgaagag gaagaaatca aactggagat
      301 aaatatgcta aagaaatact ctcatcacag aaacattgca acatattatg gtgctttcat
      361 caaaaagagc cctccaggac atgatgacca actctggctt gttatggagt tctgtggggc
      421 tgggtccatt acagaccttg tgaagaacac caaagggaac acactcaaag aagactggat
      481 cgcttacatc tccagagaaa tcctgagggg actggcacat cttcacattc atcatgtgat
      541 tcaccgggat atcaagggcc agaatgtgtt gctgactgag aatgcagagg tgaaacttgt
      601 tgactttggt gtgagtgctc agctggacag gactgtgggg cggagaaata cgttcatagg
      661 cactccctac tggatggctc ctgaggtcat cgcctgtgat gagaacccag atgccaccta
      721 tgattacaga agtgatcttt ggtcttgtgg cattacagcc attgagatgg cagaagtgct
      781 ccccctctct gtgacatgca tccaatgaga gcactgtttc tcattcccag aaaccctcct
      841 ccccggctga agtcaaaaaa atggtcgaag aagt
//
