LOCUS       sequence-10837-e         937 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 937)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 937)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-DGKK
FEATURES             Location/Qualifiers
     source          1..937
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     protein_bind    70..94
                     /gene="mutant version of attB"
                     /label=attB1
                     /bound_moiety="BP Clonase(TM)"
                     /note="recombination site for the Gateway(R) BP reaction"
     CDS             747..758
                     /codon_start=1
                     /product="Factor Xa recognition and cleavage site"
                     /label=Factor Xa site
                     /translation="IEGR"
ORIGIN
        1 aaggatttat tttgactgat agtgacctgt tcgttgcaac aaattgatga gcaatgcttt
       61 tttataatgc caactttgta caaaaaagtt ggcaccatgg accgcggagc tgccgcagcc
      121 cagggcactg ccccgcctca ggatggagag cagcccgctg agtctccaga gcctccgccg
      181 ccttggccgc cgccgccacc accaccggct ccgccgccgg ctccgccgct gctctccgag
      241 gcttcgccag aacccatacc agagccctgt ccagagcttg ctccaggtcc ctgtccagag
      301 gcgacctcag aatcagccac agaactgtac acagaaccga ccccagaacc agccacagag
      361 ccggcctcag aaccggcccc agaacctgcc acagagccgg ccccagaacc tgccacagag
      421 ccggccccag aaccggcccc agaacctgcc acagagtctg ccccagagcc gactccagaa
      481 cctgccctag agtcggtccc agagccggcc ccagagctga ctccagaagt tgccccagag
      541 ctggccccag agccgacccc agaacctgtg acagagctgg ccccagagtt ctgccctgag
      601 gcggctccag agttccgtcc aagtccagca ccatgtctat tgcaatgtcc ggtggacact
      661 cgagagagag gtctaaagac ctcgccatcg ccatcgccat cgccatcgcc cagaacgcca
      721 atgtcgtggt ccagaataaa gaaaatattg aaggaaggac ctatgctgaa gaactgtaac
      781 tctttcagag atggaagctt agatattttc tggttcaagg acagaagctc tactttgcac
      841 accatcccgc gtttgcacac tttgaaacga ttgatctgtc tcaagccact ggtggcagaa
      901 aggcagctgt agaaaccctt tggccaacag gattgtt
//
