LOCUS       sequence-10879-e         450 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 450)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 450)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-CALM3
FEATURES             Location/Qualifiers
     source          1..450
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     CDS             1..450
                     /codon_start=1
                     /product="calcium-binding protein"
                     /label=calmodulin
                     /translation="MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPT
                     EAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAA
                     ELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK"
ORIGIN
        1 atggctgacc agctgactga ggagcagatt gcagagttca aggaggcctt ctccctcttt
       61 gacaaggatg gagatggcac tatcaccacc aaggagttgg ggacagtgat gagatccctg
      121 ggacagaacc ccactgaagc agagctgcag gatatgatca atgaggtgga tgcagatggg
      181 aacgggacca ttgacttccc ggagttcctg accatgatgg ccagaaagat gaaggacaca
      241 gacagtgagg aggagatccg agaggcgttc cgtgtctttg acaaggatgg gaatggctac
      301 atcagcgccg cagagctgcg tcacgtaatg acgaacctgg gggagaagct gaccgatgag
      361 gaggtggatg agatgatcag ggaggctgac atcgatggag atggccaggt caattatgaa
      421 gagtttgtac agatgatgac tgcaaagtga
//
