LOCUS       sequence-10883-e        2052 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 2052)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 2052)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-PRKCH
FEATURES             Location/Qualifiers
     source          1..2052
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 atgtcgtctg gcaccatgaa gttcaatggc tatttgaggg tccgcatcgg tgaggcagtg
       61 gggctgcagc ccacccgctg gtccctgcgc cactcgctct tcaagaaggg ccaccagctg
      121 ctggacccct atctgacggt gagcgtggac caggtgcgcg tgggccagac cagcaccaag
      181 cagaagacca acaaacccac gtacaacgag gagttttgcg ctaacgtcac cgacggcggc
      241 cacctcgagt tggccgtctt ccacgagacg cccctgggct acgaccactt cgtggccaac
      301 tgcaccctgc agttccagga gctgctgcgc acgaccggcg cctcggacac cttcgagggt
      361 tgggtggatc tcgagccaga ggggaaagta ttcgtggtaa taacccttac cgggagtttc
      421 actgaagcta ctctccagag agaccggatc ttcaaacatt ttaccaggaa gcgccaaagg
      481 gctatgcgaa ggcgagtcca ccagatcaat ggacacaagt tcatggccac gtatctgagg
      541 cagcccacct actgctctca ctgcagggag tttatctggg gagtgtttgg gaaacagggt
      601 tatcagtgcc aagtgtgcac ctgtgtcgtc cataaacgct gccatcatct aattgttaca
      661 gcctgtactt gccaaaacaa tattaacaaa gtggattcaa agattgcaga acagaggttc
      721 gggatcaaca tcccacacaa gttcagcatc cacaactaca aagtgccaac attctgcgat
      781 cactgtggct cactgctctg gggaataatg cgacaaggac ttcagtgtaa aatatgtaaa
      841 atgaatgtgc atattcgatg tcaagcgaac gtggccccta actgtggggt aaatgcggtg
      901 gaacttgcca agaccctggc agggatgggt ctccaacccg gaaatatttc tccaacctcg
      961 aaactcgttt ccagatcgac cctaagacga cagggaaagg agagcagcaa agaaggaaat
     1021 gggattgggg ttaattcttc caaccgactt ggtatcgaca actttgagtt catccgagtg
     1081 ttggggaagg ggagttttgg gaaggtgatg cttgcaagag taaaagaaac aggagacctc
     1141 tatgctgtga aggtgctgaa gaaggacgtg attctgcagg atgatgatgt ggaatgcacc
     1201 atgaccgaga aaaggatcct gtctctggcc cgcaatcacc ccttcctcac tcagttgttc
     1261 tgctgctttc agacccccga tcgtctgttt tttgtgatgg agtttgtgaa tgggggtgac
     1321 ttgatgttcc acattcagaa gtctcgtcgt tttgatgaag cacgagctcg cttctatgct
     1381 gcagaaatca tttcggctct catgttcctc catgataaag gaatcatcta tagagatctg
     1441 aaactggaca atgtcctgtt ggaccacgag ggtcactgta aactggcaga cttcggaatg
     1501 tgcaaggagg ggatttgcaa tggtgtcacc acggccacat tctgtggcac gccagactat
     1561 atcgctccag agatcctcca ggaaatgctg tacgggcctg cagtagactg gtgggcaatg
     1621 ggcgtgttgc tctatgagat gctctgtggt cacgcgcctt ttgaggcaga gaatgaagat
     1681 gacctctttg aggccatact gaatgatgag gtggtctacc ctacctggct ccatgaagat
     1741 gccacaggga tcctaaaatc tttcatgacc aagaacccca ccatgcgctt gggcagcctg
     1801 actcagggag gcgagcacgc catcttgaga catccttttt ttaaggaaat cgactgggcc
     1861 cagctgaacc atcgccaaat agaaccgcct ttcagaccca gaatcaaatc ccgagaagat
     1921 gtcagtaatt ttgaccctga cttcataaag gaagagccag ttttaactcc aattgatgag
     1981 ggacatcttc caatgattaa ccaggatgag tttagaaact tttcctatgt gtctccagaa
     2041 ttgcaaccat ag
//
