LOCUS       sequence-10885-e        1971 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 1971)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 1971)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-AK7
FEATURES             Location/Qualifiers
     source          1..1971
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 atggctgaag aagaggaaac tgctgctctc acggagaagg ttatccggac ccagagggtg
       61 tttataaacc tgttggattc ctacagcagc ggaaacatcg ggaagtttct atctaactgt
      121 gtagttgggg cttcgcttga agaaattaca gaggaagagg aagaggaaga tgaaaataag
      181 tcagctatgc tggaagcttc ctcaaccaag gtgaaggaag gcacattcca gattgtgggc
      241 acgctgtcca agcctgacag cccgcggcct gactttgcgg tggagacgta ctctgccatc
      301 tctcgagaag accttctcat gcgcctgctg gagtgtgatg ttattattta taacatcact
      361 gagagctcac agcaaatgga ggaagccatc tgggcagtct ctgcactcag tgaagaagtc
      421 agccactttg aaaagcgaaa gctatttatt ttactgtcga cggtgatgac ttgggcgcgc
      481 tccaaagccc tggaccccga ggattctgag gttccattca ctgaagaaga ttatcgaaga
      541 agaaagtctc atcctaattt tctggaccac ataaatgctg aaaaaatggt tctcaaattt
      601 ggaaaaaagg ccagaaaatt tgcagcatac gtagttgctg ctggactcca gtatggagcg
      661 gaaggaggca tgttacacac attttttaag atggcttggt tgggcgagat tcctgcatta
      721 ccagtttttg gcgatggaac aaatgtaatt ccaacaatcc atgttcttga tctagcagga
      781 gtgatacaaa acgtcataga tcacgtgcca aagcctcact acctggttgc tgtggatgag
      841 tctgttcata ccctggaaga catagtcaag tgtatcagta aaaatactgg ccctgggaaa
      901 atccagaaaa tacccagaga aaatgcatac ctaaccaagg acttaacgca agattgtctt
      961 gaccatttac tggtcaactt gagaatggaa gcgctctttg tgaaggagaa ttttaatatt
     1021 cgatgggctg cccaaacagg atttgtggaa aatatcaaca ctatcctcaa ggagtacaag
     1081 caaagcagag gattgatgcc aatcaagatc tgcattcttg gtccccctgc tgtgggaaaa
     1141 tccagtattg ctaaagaatt ggccaagtac tacaaactgc atcacatcca actgaaggat
     1201 gtcatttctg aagccatagc aaaactggag gcgattgttg cccctaacga tgtaggggaa
     1261 ggagaagaag aagtcgaaga ggaagaggag gaggagaatg tggaagatgc acaggagctc
     1321 ctagatggca tcaaggagag catggagcag aatgcaggtc aactagacga tcaatatata
     1381 attagattta tgaaagaaaa gctaaaatca atgccttgca ggaatcaagg ttatattttg
     1441 gatggattcc caaagaccta tgatcaagca aaagacctgt tcaatcagga agatgaggag
     1501 gaggaagatg atgtcagagg cagaatgttt ccctttgata aattaattat acctgaattc
     1561 gtttgtgcac tggatgcttc ggatgagttt ctgaaggagc gtgtgataaa ccttcctgag
     1621 agcatcgtgg cggggaccca ctacagccaa gaccgattcc tccgggctct gagcaactac
     1681 cgggacatca atatcgacga tgagactgtc ttcaactatt ttgatgaact tgaaattcac
     1741 ccgatacata ttgatgtagg aaaacttgaa gatgctcaga atagacttgc tatcaaacag
     1801 ctcatcaaag agactgggga gcctcgaaat tatggtttaa cagacgaaga aaaggcagaa
     1861 gaggagcgga aggctgcgga ggagcggctg gccagggagg ctgctgagga agcagaacgc
     1921 gagcaccagg aggccgtgga gatggcagag aagatagctc gctgggagta g
//
