LOCUS       sequence-10918-e        2772 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 2772)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 2772)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-HK3
FEATURES             Location/Qualifiers
     source          1..2772
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 atggactcca ttgggtcttc agggttgcgg cagggggaag aaaccctgag ttgctctgag
       61 gagggcttgc ccgggccctc agacagctca gagctggtgc aggagtgcct gcagcagttc
      121 aaggtgacaa gggcacagct acagcagatc caagccagcc tcttgggttc catggagcag
      181 gcgctgaggg gacaggccag ccctgcccct gcggtccgga tgctgcctac atacgtgggg
      241 tccaccccac atggcactga gcaaggagac ttcgtggtgc tggagctggg ggccacaggg
      301 gcctcactgc gtgttttgtg ggtgactcta actggcattg aggggcatag ggtggagccc
      361 agaagccagg agtttgtgat cccccaagag gtgatgctgg gtgctggcca gcagctcttt
      421 gactttgctg cccactgcct gtctgagttc ctggatgcgc agcctgtgaa caaacagggt
      481 ctgcagcttg gcttcagctt ctctttccct tgtcaccaga cgggcttgga caggagcacc
      541 ctcatttcct ggaccaaagg ttttaggtgc agtggtgtgg aaggccagga tgtggtccag
      601 ctgctgagag atgccattcg gaggcagggg gcctacaaca tcgacgtggt tgctgtggtg
      661 aacgacacag tgggcaccat gatgggctgt gagccggggg tcaggccgtg tgaggttggg
      721 ctagttgtag acacgggcac caacgcgtgt tacatggagg aggcacggca tgtggcagtg
      781 ctggacgaag accggggccg cgtctgcgtc agcgtcgagt ggggctcctt cagcgatgat
      841 ggggcgctgg gaccagtgct gaccaccttc gaccataccc tggaccatga gtccctgaat
      901 cctggtgctc agaggtttga gaagatgatc ggaggcctgt acctgggtga gctggtgcgg
      961 ctggtgctgg ctcacttggc ccggtgtggg gtcctctttg gtggctgcac ctcccctgcc
     1021 ctgctgagcc aaggcagcat cctcctggaa cacgtggctg agatggagga cccctctact
     1081 ggggcagccc gtgtccatgc tatcctgcag gacttgggcc tgagccctgg ggcttcggat
     1141 gttgagcttg tgcagcacgt ctgtgcggcc gtgtgcacgc gggctgccca gctctgtgct
     1201 gccgccctgg ccgctgttct ctcctgcctc cagcacagcc gggagcaaca aacactccag
     1261 gttgctgtgg ccaccggagg ccgagtgtgt gagcggcacc ccaggttctg cagcgtcctg
     1321 caggggacag tgatgctcct ggccccggaa tgcgatgtct ccttaatccc ctctgtggat
     1381 ggtggtggcc ggggagtggc gatggtgact gctgtggctg cccgtctggc tgcccaccgg
     1441 cgcctgctgg aggagaccct ggccccattc cggttgaacc atgatcaact ggctgcggtt
     1501 caggcacaga tgcggaaggc catggccaag gggctccgag gggaggcctc ctcccttcgc
     1561 atgctgccca ctttcgtccg ggccacccct gatggcagcg agcgagggga tttcctggcc
     1621 ctggacctcg ggggcacgaa cttccgtgtc ctcctggtac gtgtgaccac aggcgtgcag
     1681 atcaccagcg agatctactc cattcccgag actgtggccc agggttctgg gcagcagctc
     1741 tttgaccaca tcgtggactg catcgtggac ttccagcaga agcagggcct gagcgggcag
     1801 agcctcccac tgggttttac cttctccttc ccatgtaggc agcttggcct agaccagggc
     1861 atcctcctga actggaccaa gggtttcaag gcatcagact gcgagggcca agatgtcgtg
     1921 agtctgttgc gggaagccat cactcgcaga caggcagtgg agctgaatgt ggttgccatt
     1981 gtcaatgaca cggtggggac catgatgtcc tgtggctatg aggacccccg ttgcgagata
     2041 ggcctcattg tcggaaccgg caccaatgcc tgctacatgg aggagctccg gaatgtggcg
     2101 ggcgtgcctg gggactcagg ccgcatgtgc atcaacatgg agtggggcgc ctttggggac
     2161 gatggctctc tggccatgct cagcacccgc tttgatgcaa gtgtggacca ggcgtccatc
     2221 aaccccggca agcagaggtt tgaaaagatg atcagcggca tgtacctggg ggagatcgtc
     2281 cgccacatcc ttttacattt aaccagcctt ggcgttctct tccggggcca gcagatccag
     2341 cgccttcaga ccagggacat cttcaagacc aagttcctct ctgagatcga aagtgacagc
     2401 ctggccctgc ggcaggtccg agccatccta gaggatctgg ggctacccct gacctcagat
     2461 gacgccctga tggtgctaga ggtgtgccag gctgtgtccc agagggctgc ccagctctgt
     2521 ggggcgggtg tagctgccgt ggtggagaag atccgggaga accggggcct ggaagagctg
     2581 gcagtgtctg tgggggtgga tggaacgctc tacaagctgc acccgcgctt ctccagcctg
     2641 gtggcggcca cagtgcggga gctggcccct cgctgtgtgg tcacgttcct gcagtcagag
     2701 gatgggtccg gcaaaggtgc ggccctggtc accgctgttg cctgccgcct tgcgcagttg
     2761 actcgtgtct ga
//
