LOCUS       sequence-10919-e        2754 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 2754)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 2754)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-HK1
FEATURES             Location/Qualifiers
     source          1..2754
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 atgatcgccg cgcagctcct ggcctattac ttcacggagc tgaaggatga ccaggtcaaa
       61 aagattgaca agtatctgta tgccatgcgg ctctccgatg aaactctcat agatatcatg
      121 actcgcttca ggaaggagat gaagaatggc ctctcccggg attttaatcc aacagccaca
      181 gtcaagatgt tgccaacatt cgtaaggtcc attcctgatg gctctgaaaa gggagatttc
      241 attgccctgg atcttggtgg gtcttccttt cgaattctgc gggtgcaagt gaatcatgag
      301 aaaaaccaga atgttcacat ggagtccgag gtttatgaca ccccagagaa catcgtgcac
      361 ggcagtggaa gccagctttt tgatcatgtt gctgagtgcc tgggagattt catggagaaa
      421 aggaagatca aggacaagaa gttacctgtg ggattcacgt tttcttttcc ttgccaacaa
      481 tccaaaatag atgaggccat cctgatcacc tggacaaagc gatttaaagc gagcggagtg
      541 gaaggagcag atgtggtcaa actgcttaac aaagccatca aaaagcgagg ggactatgat
      601 gccaacatcg tagctgtggt gaatgacaca gtgggcacca tgatgacctg tggctatgac
      661 gaccagcact gtgaagtcgg cctgatcatc ggcactggca ccaatgcttg ctacatggag
      721 gaactgaggc acattgatct ggtggaagga gacgagggga ggatgtgtat caatacagaa
      781 tggggagcct ttggagacga tggatcatta gaagacatcc ggacagagtt tgacagggag
      841 atagaccggg gatccctcaa ccctggaaaa cagctgtttg agaagatggt cagtggcatg
      901 tacttgggag agctggttcg actgatccta gtcaagatgg ccaaggaggg cctcttattt
      961 gaagggcgga tcaccccgga gctgctcacc cgagggaagt ttaacaccag tgatgtgtca
     1021 gccatcgaaa agaataagga aggcctccac aatgccaaag aaatcctgac ccgcctggga
     1081 gtggagccgt ccgatgatga ctgtgtctca gtccagcacg tttgcaccat tgtctcattt
     1141 cgctcagcca acttggtggc tgccacactg ggcgccatct tgaaccgcct gcgtgataac
     1201 aagggcacac ccaggctgcg gaccacggtt ggtgtcgacg gatctcttta caagacgcac
     1261 ccacagtatt cccggcgttt ccacaagact ctaaggcgct tggtgccaga ctccgatgtg
     1321 cgcttcctcc tctcggagag tggcagcggc aagggggctg ccatggtgac ggcggtggcc
     1381 taccgcttgg ccgagcagca ccggcagata gaggagaccc tggctcattt ccacctcacc
     1441 aaagacatgc tgctggaggt gaagaagagg atgcgggccg agatggagct ggggctgagg
     1501 aagcagacgc acaacaatgc cgtggttaag atgctgccct ccttcgtccg gagaactccc
     1561 gacgggaccg agaatggtga cttcttggcc ctggatcttg gaggaaccaa tttccgtgtg
     1621 ctgctggtga aaatccgtag tgggaaaaag agaacggtgg aaatgcacaa caagatctac
     1681 gccattccta ttgaaatcat gcagggcact ggggaagagc tgtttgatca cattgtctcc
     1741 tgcatctctg acttcttgga ctacatgggg atcaaaggcc ccaggatgcc tctgggcttc
     1801 acgttctcat ttccctgcca gcagacgagt ctggacgcgg gaatcttgat cacgtggaca
     1861 aagggtttta aggcaacaga ctgcgtgggc cacgatgtag tcaccttact aagggatgcg
     1921 ataaaaagga gagaggaatt tgacctggac gtggtggctg tggtcaacga cacagtgggc
     1981 accatgatga cctgtgctta tgaggagccc acctgtgagg ttggactcat tgttgggacc
     2041 ggcagcaatg cctgctacat ggaggagatg aagaacgtgg agatggtgga gggggaccag
     2101 gggcagatgt gcatcaacat ggagtggggg gcctttgggg acaacgggtg tctggatgat
     2161 atcaggacac actacgacag actggtggac gaatattccc taaatgctgg gaaacaaagg
     2221 tatgagaaga tgatcagtgg tatgtacctg ggtgaaatcg tccgcaacat cttaatcgac
     2281 ttcaccaaga agggattcct cttccgaggg cagatctctg agacgctgaa gacccggggc
     2341 atctttgaga ccaagtttct ctctcagatc gagagtgacc gattagcact gctccaggtc
     2401 cgggctatcc tccagcagct aggtctgaat agcacctgcg atgacagtat cctcgtcaag
     2461 acagtgtgcg gggtggtgtc caggagggcc gcacagctgt gtggcgcagg catggctgcg
     2521 gttgtggata agatccgcga gaacagagga ctggaccgtc tgaatgtgac tgtgggagtg
     2581 gacgggacac tctacaagct tcatccacac ttctccagaa tcatgcacca gacggtgaag
     2641 gaactgtcac caaaatgtaa cgtgtccttc ctcctgtctg aggatggcag cggcaagggg
     2701 gccgccctca tcacggccgt gggcgtgcgg ttacgcacag aggcaagcag ctaa
//
