LOCUS       sequence-10922-e        2301 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 2301)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 2301)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-TLK1
FEATURES             Location/Qualifiers
     source          1..2301
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 atgagtgtcc aaagtagcag tggaagtttg gaggggccgc catcttggtc ccagctctcc
       61 acgtctccaa ccccgggctc ggcggcggcg gccaggtccc tgctgaatca cacgccgcca
      121 tccgggaggc ccagggaagg tgcaatggat gagcttcata gtctggatcc aagaaggcaa
      181 gagttattgg aagctagatt tactggagtt gcaagtggga gcactggaag tacgggcagt
      241 tgcagtgttg gagctaaagc ctcaacaaat aacgaaagct ctaatcacag ttttggaagc
      301 ttgggatctt taagtgacaa agaatcagag acaccggaga agaaacaatc ggaatcatcc
      361 aggggaagaa agagaaaagc agaaaaccag aatgaaagta gtcagggaaa aagtattggg
      421 ggacgtggcc acaaaattag cgactatttt gaataccagg gtggaaatgg ctcaagtcca
      481 gtaagaggca tacctcctgc aatccgttct cctcaaaatt cacattcaca ttccactcct
      541 tcctcatctg ttcgaccgaa tagcccttct cctactgcat tagcatttgg ggaccaccct
      601 attgtacaac caaagcaatt atcctttaaa attattcaga ctgatctcac aatgctgaaa
      661 ttagcagcat tagaaagtaa taaaatccag gacctggaaa agaaggaggg acgtatagat
      721 gatttgctca gggctaactg tgatctcaga cggcaaatag atgaacaaca aaaattactt
      781 gaaaaataca aagaacgatt aaataagtgc atatcaatga gcaagaaact tcttattgaa
      841 aagagtacac aagaaaagct gtcaagcaga gagaagagta tgcaagatcg attacgcctt
      901 gggcacttta caacagttag acatggcgct tcatttactg aacaatggac agatggtttt
      961 gcatttcaga atcttgtgaa gcaacaagaa tgggtgaatc agcaaaggga agatattgaa
     1021 aggcaaagga aacttctagc caaacgcaaa cctcccacag ctaataattc tcaggcaccc
     1081 tctaccaatt ctgaaccaaa acaaaggaaa aacaaagcag tcaatggagc agagaatgat
     1141 ccctttgtta gaccaaattt accacaactg ttgactttgg cagaatatca tgaacaggaa
     1201 gaaattttca aacttagact aggacatctc aaaaaggaag aggcagaaat ccaggcagaa
     1261 cttgaacgtt tggaaagagt cagaaatctt cacatacgtg agctgaaaag aataaacaat
     1321 gaagataatt cacagttcaa agatcaccca acattaaatg aaagatattt attacttcat
     1381 ctgcttggta gaggtggctt tagtgaagtg tataaggctt ttgaccttta tgaacaaaga
     1441 tatgctgctg tgaagataca tcagcttaat aaaagctgga gagatgagaa gaaagaaaac
     1501 taccacaaac atgcctgcag agagtataga atacacaaag aactggatca ccccagaata
     1561 gttaaactct atgattattt ctccttggat acagatacgt tttgtacagt gttagaatac
     1621 tgtgaaggca atgacttgga tttctatctg aagcaacaca agttaatgtc agagaaagaa
     1681 gctcggtcta ttgtaatgca gattgtaaat gcactaagat atctcaatga gatcaaaccc
     1741 cctattatac attatgatct taagccagga aacatcctac tggtagatgg aacagcatgt
     1801 ggtgaaatca aaatcactga ttttggtctg tccaagatta tggatgatga tagctatggt
     1861 gtagatggaa tggatctaac ttcccagggg gcaggcactt actggtattt acctcctgag
     1921 tgttttgtag ttggaaaaga gccaccaaag atttccaaca aggttgatgt atggtcggtt
     1981 ggagtcatct tctttcagtg tctttatggt agaaagccat ttggtcacaa tcaatctcaa
     2041 caagacattc ttcaagaaaa tacaatatta aaagccacag aagtccagtt ccctgtaaaa
     2101 ccggttgtaa gcagtgaagc caaggcattt ataagacgct gtttggcata tcgaaaagaa
     2161 gatcgatttg atgtgcacca gctggcaaat gacccatacc ttctcccaca catgagaaga
     2221 tcaaattctt caggaaacct acacatggct gggctgacag catcccctac acccccttct
     2281 tcaagcataa ttacttactg a
//
