LOCUS       sequence-10925-e        1779 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 1779)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 1779)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-PRKCZ
FEATURES             Location/Qualifiers
     source          1..1779
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 atgcccagca ggaccggccc caagatggaa gggagcggcg gccgcgtccg cctcaaggcg
       61 cattacgggg gggacatctt catcaccagc gtggacgccg ccacgacctt cgaggagctc
      121 tgtgaggaag tgagagacat gtgtcgtctg caccagcagc acccgctcac cctcaagtgg
      181 gtggacagcg aaggtgaccc ttgcacggtg tcctcccaga tggagctgga agaggctttc
      241 cgcctggccc gtcagtgcag ggatgaaggc ctcatcattc atgttttccc gagcacccct
      301 gagcagcctg gcctgccatg tccgggagaa gacaaatcta tctaccgccg gggagccaga
      361 agatggagga agctgtaccg tgccaacggc cacctcttcc aagccaagcg ctttaacagg
      421 agagcgtact gcggtcagtg cagcgagagg atatggggcc tcgcgaggca aggctacagg
      481 tgcatcaact gcaaactgct ggtccataag cgctgccacg gcctcgtccc gctgacctgc
      541 aggaagcata tggattctgt catgccttcc caagagcctc cagtagacga caagaacgag
      601 gacgccgacc ttccttccga ggagacagat ggaattgctt acatttcctc atcccggaag
      661 catgacagca ttaaagacga ctcggaggac cttaagccag ttatcgatgg gatggatgga
      721 atcaaaatct ctcaggggct tgggctgcag gactttgacc taatcagagt catcgggcgc
      781 gggagctacg ccaaggttct cctggtgcgg ttgaagaaga atgaccaaat ttacgccatg
      841 aaagtggtga agaaagagct ggtgcatgat gacgaggata ttgactgggt acagacagag
      901 aagcacgtgt ttgagcaggc atccagcaac cccttcctgg tcggattaca ctcctgcttc
      961 cagacgacaa gtcggttgtt cctggtcatt gagtacgtca acggcgggga cctgatgttc
     1021 cacatgcaga ggcagaggaa gctccctgag gagcacgcca ggttctacgc ggccgagatc
     1081 tgcatcgccc tcaacttcct gcacgagagg gggatcatct acagggacct gaagctggac
     1141 aacgtcctcc tggatgcgga cgggcacatc aagctcacag actacggcat gtgcaaggaa
     1201 ggcctgggcc ctggtgacac aacgagcact ttctgcggaa ccccgaatta catcgccccc
     1261 gaaatcctgc ggggagagga gtacgggttc agcgtggact ggtgggcgct gggagtcctc
     1321 atgtttgaga tgatggccgg gcgctccccg ttcgacatca tcaccgacaa cccggacatg
     1381 aacacagagg actacctttt ccaagtgatc ctggagaagc ccatccggat cccccggttc
     1441 ctgtccgtca aagcctccca tgttttaaaa ggatttttaa ataaggaccc caaagagagg
     1501 ctcggctgcc ggccacagac tggattttct gacatcaagt cccacgcgtt cttccgcagc
     1561 atagactggg acttgctgga gaagaagcag gcgctccctc cattccagcc acagatcaca
     1621 gacgactacg gtctggacaa ctttgacaca cagttcacca gcgagcccgt gcagctgacc
     1681 ccagacgatg aggatgccat aaagaggatc gaccagtcag agttcgaagg ctttgagtat
     1741 atcaacccat tattgctgtc caccgaggag tcggtgtga
//
