LOCUS       sequence-10945-e         868 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 868)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 868)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-IRAK2
FEATURES             Location/Qualifiers
     source          1..868
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     protein_bind    69..93
                     /gene="mutant version of attB"
                     /label=attB1
                     /bound_moiety="BP Clonase(TM)"
                     /note="recombination site for the Gateway(R) BP reaction"
ORIGIN
        1 ttgatttatt ttgactgata gtgacctgtt cgttgcaaca aattgatgag caatgctttt
       61 ttataatgcc aactttgtac aaaaaagttg gcaccatggc ctgctacatc taccagctgc
      121 cctcctgggt gctggacgac ctgtgccgca acatggacgc gctcagcgag tgggactgga
      181 tggagttcgc ctcctacgtg atcacagacc tgacccagct gcggaagatc aagtccatgg
      241 agcgggtgca gggtgtgagc atcacgcggg agctgctgtg gtggtggggc atgcggcagg
      301 ccaccgtcca gcaacttgtg gacctcctgt gccgcctgga gctctaccgg gctgcccaga
      361 tcatcctgaa ctggaaaccg gctcctgaaa tcaggtgtcc cattccagcc ttccctgact
      421 ctgtgaagcc agaaaagcct ttggcagctt ctgtaagaaa ggctgaggat gaacaggaag
      481 aggggcagcc tgtgaggatg gccacctttc caggcccagg gtcctctcca gccagagccc
      541 accagccggc ctttctccag cctcctgaag aagatgcccc tcattccttg agaagcgacc
      601 tccccacttc gtctgattca aaggacttca gcacctccat tcctaagcag gaaaaacttt
      661 tgagcttggc tggagacagc cttttctgga gtgaggcaga cgtggtccag gcaaccgatg
      721 acttcaatca aaaccgcaaa atcagccagg ggacctttgc tgacgtctac agagggcaca
      781 ggcacgggaa gccattcgtc ttcaagaagc tcagagagac agcctgttca agtccaggat
      841 caatcgaaag attcttccag cagagttg
//
