LOCUS       sequence-11011-e        3027 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 3027)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 3027)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-PTK2B
FEATURES             Location/Qualifiers
     source          1..3027
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 atgtctgggg tgtccgagcc cctgagtcga gtaaagttgg gcacgttacg ccggcctgaa
       61 ggccctgcag agcccatggt ggtggtacca gtagatgtgg aaaaggagga cgtgcgtatc
      121 ctcaaggtct gcttctatag caacagcttc aatcctggga aaaacttcaa actggtcaaa
      181 tgcactgtcc agacggagat ccgggagatc atcacctcca tcctgctgag cgggcggatc
      241 gggcccaaca tccggttggc tgagtgctat gggctgaggc tgaagcacat gaagtccgat
      301 gagatccact ggctgcaccc acagatgaca gtgggtgagg tgcaggacaa gtatgagtgt
      361 ctgcacgtgg aagccgagtg gaggtatgac cttcaaatcc gctacttgcc agaagacttc
      421 atggagagcc tgaaggagga caggaccacg ctgctctatt tttaccaaca gctccggaac
      481 gactacatgc agcgctacgc cagcaaggtc agcgagggca tggccctgca gctgggctgc
      541 ctggagctca ggcggttctt caaggatatg ccccacaatg cacttgacaa gaagtccaac
      601 ttcgagctcc tagaaaagga agtggggctg gacttgtttt tcccaaagca gatgcaggag
      661 aacttaaagc ccaaacagtt ccggaagatg atccagcaga ccttccagca gtacgcctcg
      721 ctcagggagg aggagtgcgt catgaagttc ttcaacactc tcgccggctt cgccaacatc
      781 gaccaggaga cctaccgctg tgaactcatt caaggatgga acattactgt ggacctggtc
      841 attggcccta aagggatccg ccagctgact agtcaggacg caaagcccac ctgcctggcc
      901 gagttcaagc agatcaggtc catcaggtgc ctcccgctgg aggagggcca ggcagtactt
      961 cagctgggca ttgaaggtgc cccccaggcc ttgtccatca aaacctcatc cctagcagag
     1021 gctgagaaca tggctgacct catagacggc tactgccggc tgcagggtga gcaccaaggc
     1081 tctctcatca tccatcctag gaaagatggt gagaagcgga acagcctgcc ccagatcccc
     1141 atgctaaacc tggaggcccg gcggtcccac ctctcagaga gctgcagcat agagtcagac
     1201 atctacgcag agattcccga cgaaaccctg cgaaggcccg gaggtccaca gtatggcatt
     1261 gcccgtgaag atgtggtcct gaatcgtatt cttggggaag gcttttttgg ggaggtctat
     1321 gaaggtgtct acacaaatca taaaggggag aaaatcaatg tagctgtcaa gacctgcaag
     1381 aaagactgca ctctggacaa caaggagaag ttcatgagcg aggcagtgat catgaagaac
     1441 ctcgaccacc cgcacatcgt gaagctgatc ggcatcattg aagaggagcc cacctggatc
     1501 atcatggaat tgtatcccta tggggagctg ggccactacc tggagcggaa caagaactcc
     1561 ctgaaggtgc tcaccctcgt gctgtactca ctgcagatat gcaaagccat ggcctacctg
     1621 gagagcatca actgcgtgca cagggacatt gctgtccgga acatcctggt ggcctcccct
     1681 gagtgtgtga agctggggga ctttggtctt tcccggtaca ttgaggacga ggactattac
     1741 aaagcctctg tgactcgtct ccccatcaaa tggatgtccc cagagtccat taacttccga
     1801 cgcttcacga cagccagtga cgtctggatg ttcgccgtgt gcatgtggga gatcctgagc
     1861 tttgggaagc agcccttctt ctggctggag aacaaggatg tcatcggggt gctggagaaa
     1921 ggagaccggc tgcccaagcc tgatctctgt ccaccggtcc tttataccct catgacccgc
     1981 tgctgggact acgaccccag tgaccggccc cgcttcaccg agctggtgtg cagcctcagt
     2041 gacgtttatc agatggagaa ggacattgcc atggagcaag agaggaatgc tcgctaccga
     2101 acccccaaaa tcttggagcc cacagccttc caggaacccc cacccaagcc cagccgacct
     2161 aagtacagac cccctccgca aaccaacctc ctggctccaa agctgcagtt ccaggttcct
     2221 gagggtctgt gtgccagctc tcctacgctc accagcccta tggagtatcc atctcccgtt
     2281 aactcactgc acaccccacc tctccaccgg cacaatgtct tcaaacgcca cagcatgcgg
     2341 gaggaggact tcatccaacc cagcagccga gaagaggccc agcagctgtg ggaggctgaa
     2401 aaggtcaaaa tgcggcaaat cctggacaaa cagcagaagc agatggtgga ggactaccag
     2461 tggctcaggc aggaggagaa gtccctggac cccatggttt atatgaatga taagtcccca
     2521 ttgacgccag agaaggaggt cggctacctg gagttcacag ggcccccaca gaagcccccg
     2581 aggctgggcg cacagtccat ccagcccaca gctaacctgg accggaccga tgacctggtg
     2641 tacctcaatg tcatggagct ggtgcgggcc gtgctggagc tcaagaatga gctctgtcag
     2701 ctgccccccg agggctacgt ggtggtggtg aagaatgtgg ggctgaccct gcggaagctc
     2761 atcgggagcg tggatgatct cctgccttcc ttgccgtcat cttcacggac agagatcgag
     2821 ggcacccaga aactgctcaa caaagacctg gcagagctca tcaacaagat gcggctggcg
     2881 cagcagaacg ccgtgacctc cctgagtgag gagtgcaaga ggcagatgct gacggcttca
     2941 cacaccctgg ctatggacgc caagaacctg ctcgacgctg tggaccaggc caaggttctg
     3001 gccaatctgg cccacccacc tgcagag
//
