LOCUS       sequence-11021-e        3765 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 3765)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 3765)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-ERBB2
FEATURES             Location/Qualifiers
     source          1..3765
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 atggagctgg cggccttgtg ccgctggggg ctcctcctcg ccctcttgcc ccccggagcc
       61 gcgagcaccc aagtgtgcac cggcacagac atgaagctgc ggctccctgc cagtcccgag
      121 acccacctgg acatgctccg ccacctctac cagggctgcc aggtggtgca gggaaacctg
      181 gaactcacct acctgcccac caatgccagc ctgtccttcc tgcaggatat ccaggaggtg
      241 cagggctacg tgctcatcgc tcacaaccaa gtgaggcagg tcccactgca gaggctgcgg
      301 attgtgcgag gcacccagct ctttgaggac aactatgccc tggccgtgct agacaatgga
      361 gacccgctga acaataccac ccctgtcaca ggggcctccc caggaggcct gcgggagctg
      421 cagcttcgaa gcctcacaga gatcttgaaa ggaggggtct tgatccagcg gaacccccag
      481 ctctgctacc aggacacgat tttgtggaag gacatcttcc acaagaacaa ccagctggct
      541 ctcacactga tagacaccaa ccgctctcgg gcctgccacc cctgttctcc gatgtgtaag
      601 ggctcccgct gctggggaga gagttctgag gattgtcaga gcctgacgcg cactgtctgt
      661 gccggtggct gtgcccgctg caaggggcca ctgcccactg actgctgcca tgagcagtgt
      721 gctgccggct gcacgggccc caagcactct gactgcctgg cctgcctcca cttcaaccac
      781 agtggcatct gtgagctgca ctgcccagcc ctggtcacct acaacacaga cacgtttgag
      841 tccatgccca atcccgaggg ccggtataca ttcggcgcca gctgtgtgac tgcctgtccc
      901 tacaactacc tttctacgga cgtgggatcc tgcaccctcg tctgccccct gcacaaccaa
      961 gaggtgacag cagaggatgg aacacagcgg tgtgagaagt gcagcaagcc ctgtgcccga
     1021 gtgtgctatg gtctgggcat ggagcacttg cgagaggtga gggcagttac cagtgccaat
     1081 atccaggagt ttgctggctg caagaagatc tttgggagcc tggcatttct gccggagagc
     1141 tttgatgggg acccagcctc caacactgcc ccgctccagc cagagcagct ccaagtgttt
     1201 gagactctgg aagagatcac aggttaccta tacatctcag catggccgga cagcctgcct
     1261 gacctcagcg tcttccagaa cctgcaagta atccggggac gaattctgca caatggcgcc
     1321 tactcgctga ccctgcaagg gctgggcatc agctggctgg ggctgcgctc actgagggaa
     1381 ctgggcagtg gactggccct catccaccat aacacccacc tctgcttcgt gcacacggtg
     1441 ccctgggacc agctctttcg gaacccgcac caagctctgc tccacactgc caaccggcca
     1501 gaggacgagt gtgtgggcga gggcctggcc tgccaccagc tgtgcgcccg agggcactgc
     1561 tggggtccag ggcccaccca gtgtgtcaac tgcagccagt tccttcgggg ccaggagtgc
     1621 gtggaggaat gccgagtact gcaggggctc cccagggagt atgtgaatgc caggcactgt
     1681 ttgccgtgcc accctgagtg tcagccccag aatggctcag tgacctgttt tggaccggag
     1741 gctgaccagt gtgtggcctg tgcccactat aaggaccctc ccttctgcgt ggcccgctgc
     1801 cccagcggtg tgaaacctga cctctcctac atgcccatct ggaagtttcc agatgaggag
     1861 ggcgcatgcc agccttgccc catcaactgc acccactcct gtgtggacct ggatgacaag
     1921 ggctgccccg ccgagcagag agccagccct ctgacgtcca tcatctctgc ggtggttggc
     1981 attctgctgg tcgtggtctt gggggtggtc tttgggatcc tcatcaagcg acggcagcag
     2041 aagatccgga agtacacgat gcggagactg ctgcaggaaa cggagctggt ggagccgctg
     2101 acacctagcg gagcgatgcc caaccaggcg cagatgcgga tcctgaaaga gacggagctg
     2161 aggaaggtga aggtgcttgg atctggcgct tttggcacag tctacaaggg catctggatc
     2221 cctgatgggg agaatgtgaa aattccagtg gccatcaaag tgttgaggga aaacacatcc
     2281 cccaaagcca acaaagaaat cttagacgaa gcatacgtga tggctggtgt gggctcccca
     2341 tatgtctccc gccttctggg catctgcctg acatccacgg tgcagctggt gacacagctt
     2401 atgccctatg gctgcctctt agaccatgtc cgggaaaacc gcggacgcct gggctcccag
     2461 gacctgctga actggtgtat gcagattgcc aaggggatga gctacctgga ggatgtgcgg
     2521 ctcgtacaca gggacttggc cgctcggaac gtgctggtca agagtcccaa ccatgtcaaa
     2581 attacagact tcgggctggc tcggctgctg gacattgacg agacagagta ccatgcagat
     2641 gggggcaagg tgcccatcaa gtggatggcg ctggagtcca ttctccgccg gcggttcacc
     2701 caccagagtg atgtgtggag ttatggtgtg actgtgtggg agctgatgac ttttggggcc
     2761 aaaccttacg atgggatccc agcccgggag atccctgacc tgctggaaaa gggggagcgg
     2821 ctgccccagc cccccatctg caccattgat gtctacatga tcatggtcaa atgttggatg
     2881 attgactctg aatgtcggcc aagattccgg gagttggtgt ctgaattctc ccgcatggcc
     2941 agggaccccc agcgctttgt ggtcatccag aatgaggact tgggcccagc cagtcccttg
     3001 gacagcacct tctaccgctc actgctggag gacgatgaca tgggggacct ggtggatgct
     3061 gaggagtatc tggtacccca gcagggcttc ttctgtccag accctgcccc gggcgctggg
     3121 ggcatggtcc accacaggca ccgcagctca tctaccagga gtggcggtgg ggacctgaca
     3181 ctagggctgg agccctctga agaggaggcc cccaggtctc cactggcacc ctccgaaggg
     3241 gctggctccg atgtatttga tggtgacctg ggaatggggg cagccaaggg gctgcaaagc
     3301 ctccccacac atgaccccag ccctctacag cggtacagtg aggaccccac agtacccctg
     3361 ccctctgaga ctgatggcta cgttgccccc ctgacctgca gcccccagcc tgaatatgtg
     3421 aaccagccag atgttcggcc ccagccccct tcgccccgag agggccctct gcctgctgcc
     3481 cgacctgctg gtgccactct ggaaaggccc aagactctct ccccagggaa gaatggggtc
     3541 gtcaaagacg tttttgcctt tgggggtgcc gtggagaacc ccgagtactt gacaccccag
     3601 ggaggagctg cccctcagcc ccaccctcct cctgccttca gcccagcctt cgacaacctc
     3661 tattactggg accaggaccc accagagcgg ggggctccac ccagcacctt caaagggaca
     3721 cctacggcag agaacccaga gtacctgggt ctggacgtgc cagtg
//
