LOCUS       sequence-11028-e        1860 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 1860)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 1860)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-ITK
FEATURES             Location/Qualifiers
     source          1..1860
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 atgaacaact ttatcctcct ggaagaacag ctcatcaaga aatcccaaca aaagagaaga
       61 acttctccct cgaactttaa agtccgcttc tttgtgttaa ccaaagccag cctggcatac
      121 tttgaagatc gtcatgggaa gaagcgcacg ctgaaggggt ccattgagct ctcccgaatc
      181 aaatgtgttg agattgtgaa aagtgacatc agcatcccat gccactataa atacccgttt
      241 caggtggtgc atgacaacta cctcctatat gtgtttgctc cagatcgtga gagccggcag
      301 cgctgggtgc tggcccttaa agaagaaacg aggaataata acagtttggt gcctaaatat
      361 catcctaatt tctggatgga tgggaagtgg aggtgctgtt ctcagctgga gaagcttgca
      421 acaggctgtg cccaatatga tccaaccaag aatgcttcaa agaagcctct tcctcctact
      481 cctgaagaca acaggcgacc actttgggaa cctgaagaaa ctgtggtcat tgccttatat
      541 gactaccaaa ccaatgatcc tcaggaactc gcactgcggc gcaacgaaga gtactgcctg
      601 ctggacagtt ctgagattca ctggtggaga gtccaggaca ggaatgggca tgaaggatat
      661 gtaccaagca gttatctggt ggaaaaatct ccaaataatc tggaaaccta tgagtggtac
      721 aataagagta tcagccgaga caaagctgaa aaacttcttt tggacacagg caaagaagga
      781 gccttcatgg taagggattc caggactgca ggaacataca ccgtgtctgt tttcaccaag
      841 gctgttgtaa gtgagaacaa tccctgtata aagcattatc acatcaagga aacaaatgac
      901 aatcctaagc gatactatgt ggctgaaaag tatgtgttcg attccatccc tcttctcatc
      961 aactatcacc aacataatgg aggaggcctg gtgactcgac tccggtatcc agtttgtttt
     1021 gggaggcaga aagccccagt tacagcaggg ctgagatacg ggaaatgggt gatcgacccc
     1081 tcagagctca cttttgtgca agagattggc agtgggcaat ttgggttggt gcatctgggc
     1141 tactggctca acaaggacaa ggtggctatc aaaaccattc gggaaggggc tatgtcagaa
     1201 gaggacttca tagaggaggc tgaagtaatg atgaaactct ctcatcccaa actggtgcag
     1261 ctgtatgggg tgtgcctgga gcaggccccc atctgcctgg tgtttgagtt catggagcac
     1321 ggctgcctgt cagattatct acgcacccag cggggacttt ttgctgcaga gaccctgctg
     1381 ggcatgtgtc tggatgtgtg tgagggcatg gcctacctgg aagaggcatg tgtcatccac
     1441 agagacttgg ctgccagaaa ttgtttggtg ggagaaaacc aagtcatcaa ggtgtctgac
     1501 tttgggatga caaggttcgt tctggatgat cagtacacca gttccacagg caccaaattc
     1561 ccggtgaagt gggcatcccc agaggttttc tctttcagtc gctatagcag caagtccgat
     1621 gtgtggtcat ttggtgtgct gatgtgggaa gttttcagtg aaggcaaaat cccgtatgaa
     1681 aaccgaagca actcagaggt ggtggaagac atcagtaccg gatttcggtt gtacaagccc
     1741 cggctggcct ccacacacgt ctaccagatt atgaatcact gctggaaaga gagaccagaa
     1801 gatcggccag ccttctccag actgctgcgt caactggctg aaattgcaga atcaggactt
//
