LOCUS       sequence-11035-e        4026 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 4026)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 4026)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-ERBB3
FEATURES             Location/Qualifiers
     source          1..4026
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 atgagggcga acgacgctct gcaggtgctg ggcttgcttt tcagcctggc ccggggctcc
       61 gaggtgggca actctcaggc agtgtgtcct gggactctga atggcctgag tgtgaccggc
      121 gatgctgaga accaatacca gacactgtac aagctctacg agaggtgtga ggtggtgatg
      181 gggaaccttg agattgtgct cacgggacac aatgccgacc tctccttcct gcagtggatt
      241 cgagaagtga caggctatgt cctcgtggcc atgaatgaat tctctactct accattgccc
      301 aacctccgcg tggtgcgagg gacccaggtc tacgatggga agtttgccat cttcgtcatg
      361 ttgaactata acaccaactc cagccacgct ctgcgccagc tccgcttgac tcagctcacc
      421 gagattctgt cagggggtgt ttatattgag aagaacgata agctttgtca catggacaca
      481 attgactgga gggacatcgt gagggaccga gatgctgaga tagtggtgaa ggacaatggc
      541 agaagctgtc ccccctgtca tgaggtttgc aaggggcgat gctggggtcc tggatcagaa
      601 gactgccaga cattgaccaa gaccatctgt gctcctcagt gtaatggtca ctgctttggg
      661 cccaacccca accagtgctg ccatgatgag tgtgccgggg gctgctcagg ccctcaggac
      721 acagactgct ttgcctgccg gcacttcaat gacagtggag cctgtgtacc tcgctgtcca
      781 cagcctcttg tctacaacaa gctaactttc cagctggaac ccaatcccca caccaagtat
      841 cagtatggag gagtttgtgt agccagctgt ccccataact ttgtggtgga tcaaacatcc
      901 tgtgtcaggg cctgtcctcc tgacaagatg gaagtagata aaaatgggct caagatgtgt
      961 gagccttgtg ggggactatg tcccaaagcc tgtgagggaa caggctctgg gagccgcttc
     1021 cagactgtgg actcgagcaa cattgatgga tttgtgaact gcaccaagat cctgggcaac
     1081 ctggactttc tgatcaccgg cctcaatgga gacccctggc acaagatccc tgccctggac
     1141 ccagagaagc tcaatgtctt ccggacagta cgggagatca caggttacct gaacatccag
     1201 tcctggccgc cccacatgca caacttcagt gttttttcca atttgacaac cattggaggc
     1261 agaagcctct acaaccgggg cttctcattg ttgatcatga agaacttgaa tgtcacatct
     1321 ctgggcttcc gatccctgaa ggaaattagt gctgggcgta tctatataag tgccaatagg
     1381 cagctctgct accaccactc tttgaactgg accaaggtgc ttcgggggcc tacggaagag
     1441 cgactagaca tcaagcataa tcggccgcgc agagactgcg tggcagaggg caaagtgtgt
     1501 gacccactgt gctcctctgg gggatgctgg ggcccaggcc ctggtcagtg cttgtcctgt
     1561 cgaaattata gccgaggagg tgtctgtgtg acccactgca actttctgaa tggggagcct
     1621 cgagaatttg cccatgaggc cgaatgcttc tcctgccacc cggaatgcca acccatggag
     1681 ggcactgcca catgcaatgg ctcgggctct gatacttgtg ctcaatgtgc ccattttcga
     1741 gatgggcccc actgtgtgag cagctgcccc catggagtcc taggtgccaa gggcccaatc
     1801 tacaagtacc cagatgttca gaatgaatgt cggccctgcc atgagaactg cacccagggg
     1861 tgtaaaggac cagagcttca agactgttta ggacaaacac tggtgctgat cggcaaaacc
     1921 catctgacaa tggctttgac agtgatagca ggattggtag tgattttcat gatgctgggc
     1981 ggcacttttc tctactggcg tgggcgccgg attcagaata aaagggctat gaggcgatac
     2041 ttggaacggg gtgagagcat agagcctctg gaccccagtg agaaggctaa caaagtcttg
     2101 gccagaatct tcaaagagac agagctaagg aagcttaaag tgcttggctc gggtgtcttt
     2161 ggaactgtgc acaaaggagt gtggatccct gagggtgaat caatcaagat tccagtctgc
     2221 attaaagtca ttgaggacaa gagtggacgg cagagttttc aagctgtgac agatcatatg
     2281 ctggccattg gcagcctgga ccatgcccac attgtaaggc tgctgggact atgcccaggg
     2341 tcatctctgc agcttgtcac tcaatatttg cctctgggtt ctctgctgga tcatgtgaga
     2401 caacaccggg gggcactggg gccacagctg ctgctcaact ggggagtaca aattgccaag
     2461 ggaatgtact accttgagga acatggtatg gtgcatagaa acctggctgc ccgaaacgtg
     2521 ctactcaagt cacccagtca ggttcaggtg gcagattttg gtgtggctga cctgctgcct
     2581 cctgatgata agcagctgct atacagtgag gccaagactc caattaagtg gatggccctt
     2641 gagagtatcc actttgggaa atacacacac cagagtgatg tctggagcta tggtgtgaca
     2701 gtttgggagt tgatgacctt cggggcagag ccctatgcag ggctacgatt ggctgaagta
     2761 ccagacctgc tagagaaggg ggagcggttg gcacagcccc agatctgcac aattgatgtc
     2821 tacatggtga tggtcaagtg ttggatgatt gatgagaaca ttcgcccaac ctttaaagaa
     2881 ctagccaatg agttcaccag gatggcccga gacccaccac ggtatctggt cataaagaga
     2941 gagagtgggc ctggaatagc ccctgggcca gagccccatg gtctgacaaa caagaagcta
     3001 gaggaagtag agctggagcc agaactagac ctagacctag acttggaagc agaggaggac
     3061 aacctggcaa ccaccacact gggctccgcc ctcagcctac cagttggaac acttaatcgg
     3121 ccacgtggga gccagagcct tttaagtcca tcatctggat acatgcccat gaaccagggt
     3181 aatcttgggg agtcttgcca ggagtctgca gtttctggga gcagtgaacg gtgcccccgt
     3241 ccagtctctc tacacccaat gccacgggga tgcctggcat cagagtcatc agaggggcat
     3301 gtaacaggct ctgaggctga gctccaggag aaagtgtcaa tgtgtaggag ccggagcagg
     3361 agccggagcc cacggccacg cggagatagc gcctaccatt cccagcgcca cagtctgctg
     3421 actcctgtta ccccactctc cccacccggg ttagaggaag aggatgtcaa cggttatgtc
     3481 atgccagata cacacctcaa aggtactccc tcctcccggg aaggcaccct ttcttcagtg
     3541 ggtctcagtt ctgtcctggg tactgaagaa gaagatgaag atgaggagta tgaatacatg
     3601 aaccggagga gaaggcacag tccacctcat ccccctaggc caagttccct tgaggagctg
     3661 ggttatgagt acatggatgt ggggtcagac ctcagtgcct ctctgggcag cacacagagt
     3721 tgcccactcc accctgtacc catcatgccc actgcaggca caactccaga tgaagactat
     3781 gaatatatga atcggcaacg agatggaggt ggtcctgggg gtgattatgc agccatgggg
     3841 gcctgcccag catctgagca agggtatgaa gagatgagag cttttcaggg gcctggacat
     3901 caggcccccc atgtccatta tgcccgccta aaaactctac gtagcttaga ggctacagac
     3961 tctgcctttg ataaccctga ttactggcat agcaggcttt tccccaaggc taatgcccag
     4021 agaacg
//
