LOCUS       sequence-11052-e        2574 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 2574)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 2574)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-TTK
FEATURES             Location/Qualifiers
     source          1..2574
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 atggaatccg aggatttaag tggcagagaa ttgacaattg attccataat gaacaaagtg
       61 agagacatta aaaataagtt taaaaatgaa gaccttactg atgaactaag cttgaataaa
      121 atttctgctg atactacaga taactcggga actgttaacc aaattatgat gatggcaaac
      181 aacccagagg actggttgag tttgttgctc aaactagaga aaaacagtgt tccgctaagt
      241 gatgctcttt taaataaatt gattggtcgt tacagtcaag caattgaagc gcttccccca
      301 gataaatatg gccaaaatga gagttttgct agaattcaag tgagatttgc tgaattaaaa
      361 gctattcaag agccagatga tgcacgtgac tactttcaaa tggccagagc aaactgcaag
      421 aaatttgctt ttgttcatat atcttttgca caatttgaac tgtcacaagg taatgtcaaa
      481 aaaagtaaac aacttcttca aaaagctgta gaacgtggag cagtaccact agaaatgctg
      541 gaaattgccc tgcggaattt aaacctccaa aaaaagcagc tgctttcaga ggaggaaaag
      601 aagaatttat cagcatctac ggtattaact gcccaagaat cattttccgg ttcacttggg
      661 catttacaga ataggaacaa cagttgtgat tccagaggac agactactaa agccaggttt
      721 ttatatggag agaacatgcc accacaagat gcagaaatag gttaccggaa ttcattgaga
      781 caaactaaca aaactaaaca gtcatgccca tttggaagag tcccagttaa ccttctaaat
      841 agcccagatt gtgatgtgaa gacagatgat tcagttgtac cttgttttat gaaaagacaa
      901 acctctagat cagaatgccg agatttggtt gtgcctggat ctaaaccaag tggaaatgat
      961 tcctgtgaat taagaaattt aaagtctgtt caaaatagtc atttcaagga acctctggtg
     1021 tcagatgaaa agagttctga acttattatt actgattcaa taaccctgaa gaataaaacg
     1081 gaatcaagtc ttctagctaa attagaagaa actaaagagt atcaagaacc agaggttcca
     1141 gagagtaacc agaaacagtg gcaatctaag agaaagtcag agtgtattaa ccagaatcct
     1201 gctgcatctt caaatcactg gcagattccg gagttagccc gaaaagttaa tacagagcag
     1261 aaacatacca cttttgagca acctgtcttt tcagtttcaa aacagtcacc accaatatca
     1321 acatctaaat ggtttgaccc aaaatctatt tgtaagacac caagcagcaa taccttggat
     1381 gattacatga gctgttttag aactccagtt gtaaagaatg actttccacc tgcttgtcag
     1441 ttgtcaacac cttatggcca acctgcctgt ttccagcagc aacagcatca aatacttgcc
     1501 actccacttc aaaatttaca ggttttagca tcttcttcag caaatgaatg catttcggtt
     1561 aaaggaagaa tttattccat tttaaagcag ataggaagtg gaggttcaag caaggtattt
     1621 caggtgttaa atgaaaagaa acagatatat gctataaaat atgtgaactt agaagaagca
     1681 gataaccaaa ctcttgatag ttaccggaac gaaatagctt atttgaataa actacaacaa
     1741 cacagtgata agatcatccg actttatgat tatgaaatca cggaccagta catctacatg
     1801 gtaatggagt gtggaaatat tgatcttaat agttggctta aaaagaaaaa atccattgat
     1861 ccatgggaac gcaagagtta ctggaaaaat atgttagagg cagttcacac aatccatcaa
     1921 catggcattg ttcacagtga tcttaaacca gctaactttc tgatagttga tggaatgcta
     1981 aagctaattg attttgggat tgcaaaccaa atgcaaccag atacaacaag tgttgttaaa
     2041 gattctcagg ttggcacagt taattatatg ccaccagaag caatcaaaga tatgtcttcc
     2101 tccagagaga atgggaaatc taagtcaaag ataagcccca aaagtgatgt ttggtcctta
     2161 ggatgtattt tgtactatat gacttacggg aaaacaccat ttcagcagat aattaatcag
     2221 atttctaaat tacatgccat aattgatcct aatcatgaaa ttgaatttcc cgatattcca
     2281 gagaaagatc ttcaagatgt gttaaagtgt tgtttaaaaa gggacccaaa acagaggata
     2341 tccattcctg agctcctggc tcatccctat gttcaaattc aaactcatcc agttaaccaa
     2401 atggccaagg gaaccactga agaaatgaaa tatgttctgg gccaacttgt tggtctgaat
     2461 tctcctaact ccattttgaa agctgctaaa actttatatg aacactatag tggtggtgaa
     2521 agtcataatt cttcatcctc caagactttt gaaaaaaaaa ggggaaaaaa atga
//
