LOCUS       sequence-11069-e        2421 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 2421)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 2421)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-EIF2AK4
FEATURES             Location/Qualifiers
     source          1..2421
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 atgattcacc gggatttgaa gcctgtcaac atttttttgg attctgatga ccatgtgaaa
       61 ataggtgatt ttggtttggc gacagaccat ctagcctttt ctgctgacag caaacaagac
      121 gatcagacag gagacttgat taagtcagac ccttcaggtc acttaactgg gatggttggc
      181 actgctctct atgtaagccc agaggtccaa ggaagcacca aatctgcata caaccagaaa
      241 gtggatctct tcagcctggg aattatcttc tttgagatgt cctatcaccc catggtcacg
      301 gcttcagaaa ggatctttgt tctcaaccaa ctcagagatc ccacttcgcc taagtttcca
      361 gaagactttg acgatggaga gcatgcaaag cagaaatcag tcatctcctg gctgttgaac
      421 cacgatccag caaaacggcc cacagccaca gaactgctca agagtgagct gctgccccca
      481 ccccagatgg aggagtcaga gctgcatgaa gtgctgcacc acacgctgac caacgtggat
      541 gggaaggcct accgcaccat gatggcccag atcttctcgc agcgcatctc ccctgccatc
      601 gattacacct atgacagcga catactgaag ggcaacttct caatccgtac agccaagatg
      661 cagcagcatg tgtgtgaaac catcatccgc atctttaaaa gacatggagc tgttcagttg
      721 tgtactccac tactgcttcc ccgaaacaga caaatatatg agcacaacga agctgcccta
      781 ttcatggacc acagcgggat gctggtgatg cttccttttg acctgcggat cccttttgca
      841 agatatgtgg caagaaataa tatattgaat ttaaaacgat actgcataga acgtgtgttc
      901 aggccgcgca agttagatcg atttcatccc aaagaacttc tggagtgtgc atttgatatt
      961 gtcacttcta ccaccaacag ctttctgccc actgctgaaa ttatctacac tatctatgaa
     1021 atcatccaag agtttccagc acttcaggaa agaaattaca gtatttattt gaaccatacc
     1081 atgttattga aagcaatact cttacactgt gggatcccag aagataaact cagtcaagtc
     1141 tacattattc tgtatgatgc tgtgacagag aagctgacga ggagagaagt ggaagctaaa
     1201 ttttgtaatc tgtctttgtc ttctaatagt ctgtgtcgac tctacaagtt tattgaacag
     1261 aagggagatt tgcaagatct tatgccaaca ataaattcat taataaaaca gaaaacaggt
     1321 attgcacagt tggtgaagta tggcttaaaa gacctagagg aggttgttgg actgttgaag
     1381 aaactctgca tcaagttaca ggtcttgatc aatttgggct tggtttacaa ggtgcagcag
     1441 cacaatggaa tcatcttcca gtttgtggct ttcatcaaac gaaggcaaag ggctgtacct
     1501 gaaatcctcg cagctggagg cagatatgac ctgctgattc cccagtttag agggccacaa
     1561 gctctggggc cagttcccac tgccattggg gtcagcatag ctatagacaa gatatctgct
     1621 gctgtcctca acatggagga atctgttaca ataagctctt gtgacctcct ggttgtaagt
     1681 gttggccaga tgtctatgtc cagggccatc aacctaaccc agaaactctg gacagcaggc
     1741 atcacagcag aaatcatgta cgactggtca cagtcccaag aggaattaca agagtactgc
     1801 agacatcatg aaatcaccta tgtggccctt gtctcggata aagaaggaag ccatgtcaag
     1861 gttaagtctt tcgagaagga aaggcagaca gagaagcgtg tgctggagac tgaacttgtg
     1921 gaccatgtac tgcagaaact gaggactaaa gtcactgatg aaaggaatgg cagagaagct
     1981 tccgataatc ttgcagtgca aaatctgaag gggtcatttt ctaatgcttc aggtttgttt
     2041 gaaatccatg gagcaacagt ggttcccatt gtgagtgtgc tagccccgga gaagctgtca
     2101 gccagcacta ggaggcgcta tgaaactcag gtacaaactc gacttcagac ctcccttgcc
     2161 aacttacatc agaaaagcag tgaaattgaa attctggctg tggatctacc caaagaaaca
     2221 atattacagt ttttatcatt agagtgggat gctgatgaac aggcatttaa cacaactgtg
     2281 aagcagctgc tgtcacgcct gccaaagcaa agatacctca aattagtctg tgatgaaatt
     2341 tataacatca aagtagaaaa aaaggtgtct gtgctatttc tgtacagcta tagagatgac
     2401 tactacagaa tcttatttta a
//
