LOCUS       sequence-11114-e         884 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 884)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 884)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-GSG2
FEATURES             Location/Qualifiers
     source          1..884
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     protein_bind    73..97
                     /gene="mutant version of attB"
                     /label=attB1
                     /bound_moiety="BP Clonase(TM)"
                     /note="recombination site for the Gateway(R) BP reaction"
     regulatory      98..107
                     /label=Kozak sequence
                     /note="vertebrate consensus sequence for strong initiation 
                     of translation (Kozak, 1987)"
                     /regulatory_class="other"
ORIGIN
        1 ctatggattt tattttgact gatagtgacc tgttcgttgc aacaaattga tgagcaatgc
       61 ttttttataa tgccaacttt gtacaaaaaa gttggcacca tggcggcttc gctcccggga
      121 cctgggagcc ggcttttccg cacatatggg gctgcggacg gcaggagaca gcggcggccg
      181 ggccgggaag ccgcgcagtg gttcccgccg caggaccgga ggcgtttctt caacagcagc
      241 ggcagcagcg acgccagcat cggcgacccc tcgcagtccg acgatcctga cgatcccgac
      301 gaccccgact tccccggcag cccggtgagg cggcggcgga ggcgtcccgg cggccgagtg
      361 cccaaggacc ggcccagcct gaccgtgacc ccaaagcgct ggaagctgcg agctcgccca
      421 agcctaaccg tgaccccaag acgcctgggg ctgcgagctc ggcccccgca gaagtgcagc
      481 acaccctgcg gcccgctccg acttccgccc ttccccagcc gcgactccgg ccgcctcagc
      541 ccggacctca gcgtgtgcgg ccagcccagg gacggcgacg agctgggcat cagtgcctcc
      601 ctgttcagct ctctggcctc gccctgcccc gggtccccaa cgccaaggga cagtgtcatc
      661 tcgatcggca cctccgcctg tctggttgca gcctcagccg tcccgagcgg cctccacctc
      721 ccagaagtct ccctggaccg agcatctctc ccctgctccc agaggaagcg acaggaggag
      781 ccaaggacac cagatggtcc accaacccgc gccagcctca gtcagttctc tttggcctta
      841 tgaactcagg aacccctgag gattctgagt ttcgggcaga tggg
//
