LOCUS       sequence-11157-e        1965 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 1965)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 1965)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-SPHK2
FEATURES             Location/Qualifiers
     source          1..1965
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 atgaatggac accttgaagc agaggagcag caggaccaga ggccagacca ggagctgacc
       61 gggagctggg gccacgggcc taggagcacc ctggtcaggg ctaaggccat ggccccgccc
      121 ccaccgccac tggctgccag caccccgctc ctccatggcg agtttggctc ctacccagcc
      181 cgaggcccac gctttgccct cacccttaca tcgcaggccc tgcacataca gcggctgcgc
      241 cccaaacctg aagccaggcc ccggggtggc ctggtcccgt tggccgaggt ctcaggctgc
      301 tgcaccctgc gaagccgcag cccctcagac tcagcggcct acttctgcat ctacacctac
      361 cctcggggcc ggcgcggggc ccggcgcaga gccactcgca ccttccgggc agatggggcc
      421 gccacctacg aagagaaccg tgccgaggcc cagcgctggg ccactgccct cacctgtctg
      481 ctccgaggac tgccactgcc cggggatggg gagatcaccc ctgacctgct acctcggccg
      541 ccccggttgc ttctattggt caatcccttt gggggtcggg gcctggcctg gcagtggtgt
      601 aagaaccacg tgcttcccat gatctctgaa gctgggctgt ccttcaacct catccagaca
      661 gaacgacaga accacgcccg ggagctggtc caggggctga gcctgagtga gtgggatggc
      721 atcgtcacgg tctcgggaga cgggctgctc catgaggtgc tgaacgggct cctagatcgc
      781 cctgactggg aggaagctgt gaagatgcct gtgggcatcc tcccctgcgg ctcgggcaac
      841 gcgctggccg gagcagtgaa ccagcacggg ggatttgagc cagccctggg cctcgacctg
      901 ttgctcaact gctcactgtt gctgtgccgg ggtggtggcc acccactgga cctgctctcc
      961 gtgacgctgg cctcgggctc ccgctgtttc tccttcctgt ctgtggcctg gggcttcgtg
     1021 tcagatgtgg atatccagag cgagcgcttc agggccttgg gcagtgcccg cttcacactg
     1081 ggcacggtgc tgggcctcgc cacactgcac acctaccgcg gacgcctctc ctacctcccc
     1141 gccactgtgg aacctgcctc gcccacccct gcccatagcc tgcctcgtgc caagtcggag
     1201 ctgaccctaa ccccagaccc agccccgccc atggcccact cacccctgca tcgttctgtg
     1261 tctgacctgc ctcttcccct gccccagcct gccctggcct ctcctggctc gccagaaccc
     1321 ctgcccatcc tgtccctcaa cggtgggggc ccagagctgg ctggggactg gggtggggct
     1381 ggggatgctc cgctgtcccc ggacccactg ctgtcttcac ctcctggctc tcccaaggca
     1441 gctctacact cacccgtctc cgaaggggcc cccgtaattc ccccatcctc tgggctccca
     1501 cttcccaccc ctgatgcccg ggtaggggcc tccacctgcg gcccgcccga ccacctgctg
     1561 cctccgctgg gcaccccgct gcccccagac tgggtgacgc tggaggggga ctttgtgctc
     1621 atgttggcca tctcgcccag ccacctaggc gctgacctgg tggcagctcc gcatgcgcgc
     1681 ttcgacgacg gcctggtgca cctgtgctgg gtgcgtagcg gcatctcgcg ggctgcgctg
     1741 ctgcgccttt tcttggccat ggagcgtggt agccacttca gcctgggctg tccgcagctg
     1801 ggctacgccg cggcccgtgc cttccgccta gagccgctca caccacgcgg cgtgctcaca
     1861 gtggacgggg agcaggtgga gtatgggccg ctacaggcac agatgcaccc tggcatcggt
     1921 acactgctca ctgggcctcc tggctgcccg gggcgggagc cctga
//
