LOCUS       sequence-11159-e        1650 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 1650)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 1650)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-FASTK
FEATURES             Location/Qualifiers
     source          1..1650
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     CDS             complement(1099..1110)
                     /codon_start=1
                     /product="WELQut protease recognition and cleavage site"
                     /label=WELQut site
                     /translation="WELQ"
ORIGIN
        1 atgaggaggc cgcgggggga acccggcccc cgggccccga gaccgactga gggagcgacc
       61 tgcgcagggc ccggggagtc atggtctcca tcacccaact ccatgcttcg agtcctgctc
      121 tctgctcaga cctcccctgc tcggctgtct ggcctgctgc tgatccctcc agtacagccc
      181 tgctgtttgg ggcccagcaa atggggggac cggcctgttg gaggaggccc cagtgcaggt
      241 cctgtgcaag gactgcagcg gcttctggaa caggcgaaga gccctgggga gctgctgcgc
      301 tggctgggcc agaaccccag caaggtgcgc gcccaccact actcggtggc gcttcgtcgt
      361 ctgggccagc tcttggggtc tcggccacgg ccccctcctg tggagcaggt cacactgcag
      421 gacttgagtc agctcatcat ccgaaactgc ccctcctttg acattcacac catccacgtg
      481 tgtctgcacc ttgcagtctt acttggcttt ccatctgatg gtcccctggt gtgtgccctg
      541 gaacaggagc gaaggctccg cctccctccg aagccacctc cccctttgca gccccttctc
      601 cgaggtgggc aagggttgga agctgctcta agctgccccc gttttctgcg gtatccacgg
      661 cagcatctga tcagcagcct ggcagaggca aggccagagg aactgactcc ccacgtgatg
      721 gtgctcctgg cccagcacct ggcccggcac cggttgcggg agccccagct tctggaagcc
      781 attgcccact tcctggtggt tcaggaaacg caactcagca gcaaggtggt acagaagttg
      841 gtcctgccct ttgggcgact gaactacctg cccctggaac agcagtttat gccctgcctt
      901 gagaggatcc tggctcggga agcaggggtg gcacccctgg ctacagtcaa catcttgatg
      961 tcactgtgcc aactgcggtg cctgcccttc agagccctgc actttgtttt ttcccctggc
     1021 ttcatcaact acatcagtgg cacccctcat gctctgattg tgcgtcgcta cctctccctg
     1081 ctggacacgg ccgtggagct ggagctccca ggataccggg gtccccgcct tccccgaagg
     1141 cagcaagtgc ccatctttcc ccagcctctc atcaccgacc gtgcccgctg caagtacagt
     1201 cacaaggaca tagtagctga ggggttgcgc cagctgctgg gggaggagaa ataccgccag
     1261 gacctgactg tgcctccagg ctactgcaca gacttcctgc tgtgcgccag cagctctggt
     1321 gctgtgcttc ccgtgaggac ccaggacccc ttcctgccat acccaccaag gtcctgccca
     1381 cagggccagg ctgcctctag cgccactact cgagaccctg cccagagggt ggtgctggtg
     1441 ttgcgggaac gctggcattt ctgccgggac ggccgggtgc tgctgggctc gagggccctg
     1501 agggagcggc acctaggcct gatgggctac cagctcctgc cgctaccctt cgaggaactg
     1561 gagtcccaga gaggcctgcc ccagctcaag agctacctga ggcagaagct ccaggccctg
     1621 ggcctgcgct gggggcctga agggggctga
//
