LOCUS       sequence-11175-e        1365 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 1365)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 1365)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-PIK3R1
FEATURES             Location/Qualifiers
     source          1..1365
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 atgtacaata ctgtttggaa tatggaagac ctggatttag aatatgccaa gacagatata
       61 aattgtggca cagacttgat gttttatata gaaatggacc caccagcact gcctcctaaa
      121 ccaccaaaac ctactactgt agccaacaac ggtatgaata acaatatgtc cttacaagat
      181 gctgaatggt actggggaga tatctcgagg gaagaagtga atgaaaaact tcgagataca
      241 gcagacggga cctttttggt acgagatgcg tctactaaaa tgcatggtga ttatactctt
      301 acactaagga aagggggaaa taacaaatta atcaaaatat ttcatcgaga tgggaaatat
      361 ggcttctctg acccattaac cttcagttct gtggttgaat taataaacca ctaccggaat
      421 gaatctctag ctcagtataa tcccaaattg gatgtgaaat tactttatcc agtatccaaa
      481 taccaacagg atcaagttgt caaagaagat aatattgaag ctgtagggaa aaaattacat
      541 aaatataaca ctcagtttca agaaaaaagt cgagaatatg atagattata tgaagaatat
      601 acccgcacat cccaggaaat ccaaatgaaa aggacagcta ttgaagcatt taatgaaacc
      661 ataaaaatat ttgaagaaca gtgccagacc caagagcggt acagcaaaga atacatagaa
      721 aagtttaaac gtgaaggcaa tgagaaagaa atacaaagga ttatgcataa ttatgataag
      781 ttgaagtctc gaatcagtga aattattgac agtagaagaa gattggaaga agacttgaag
      841 aagcaggcag ctgagtatcg agaaattgac aaacgtatga acagcattaa accagacctt
      901 atccagctga gaaagacgag agaccaatac ttgatgtggt tgactcaaaa aggtgttcgg
      961 caaaagaagt tgaacgagtg gttgggcaat gaaaacactg aagaccaata ttcactggtg
     1021 gaagatgatg aagatttgcc ccatcatgat gagaagacat ggaatgttgg aagcagcaac
     1081 cgaaacaaag ctgaaaacct gttgcgaggg aagcgagatg gcacttttct tgtccgggag
     1141 agcagtaaac agggctgcta tgcctgctct gtagtggtgg acggcgaagt aaagcattgt
     1201 gtcataaaca aaacagcaac tggctatggc tttgccgagc cctataactt gtacagctct
     1261 ctgaaagaac tggtgctaca ttaccaacac acctcccttg tgcagcacaa cgactccctc
     1321 aatgtcacac tagcctaccc agtatatgca cagcagaggc gatga
//
