LOCUS       sequence-11178-e        1740 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 1740)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 1740)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-MAP3K7
FEATURES             Location/Qualifiers
     source          1..1740
                     /mol_type="genomic DNA"
                     /organism="unspecified"
     CDS             complement(819..830)
                     /codon_start=1
                     /product="Factor Xa recognition and cleavage site"
                     /label=Factor Xa site
                     /translation="IEGR"
ORIGIN
        1 atgtctacag cctctgccgc ctcctcctcc tcctcgtctt cggccggtga gatgatcgaa
       61 gccccttccc aggtcctcaa ctttgaagag atcgactaca aggagatcga ggtggaagag
      121 gttgttggaa gaggagcctt tggagttgtt tgcaaagcta agtggagagc aaaagatgtt
      181 gctattaaac aaatagaaag tgaatctgag aggaaagcgt ttattgtaga gcttcggcag
      241 ttatcccgtg tgaaccatcc taatattgta aagctttatg gagcctgctt gaatccagtg
      301 tgtcttgtga tggaatatgc tgaagggggc tctttatata atgtgctgca tggtgctgaa
      361 ccattgccat attatactgc tgcccacgca atgagttggt gtttacagtg ttcccaagga
      421 gtggcttatc ttcacagcat gcaacccaaa gcgctaattc acagggacct gaaaccacca
      481 aacttactgc tggttgcagg ggggacagtt ctaaaaattt gtgattttgg tacagcctgt
      541 gacattcaga cacacatgac caataacaag gggagtgctg cttggatggc acctgaagtt
      601 tttgaaggta gtaattacag tgaaaaatgt gacgtcttca gctggggtat tattctttgg
      661 gaagtgataa cgcgtcggaa accctttgat gagattggtg gcccagcttt ccgaatcatg
      721 tgggctgttc ataatggtac tcgaccacca ctgataaaaa atttacctaa gcccattgag
      781 agcctgatga ctcgttgttg gtctaaagat ccttcccagc gcccttcaat ggaggaaatt
      841 gtgaaaataa tgactcactt gatgcggtac tttccaggag cagatgagcc attacagtat
      901 ccttgtcagt attcagatga aggacagagc aactctgcca ccagtacagg ctcattcatg
      961 gacattgctt ctacaaatac gagtaacaaa agtgacacta atatggagca agttcctgcc
     1021 acaaatgata ctattaagcg cttagaatca aaattgttga aaaatcaggc aaagcaacag
     1081 agtgaatctg gacgtttaag cttgggagcc tcccgtggga gcagtgtgga gagcttgccc
     1141 ccaacctctg agggcaagag gatgagtgct gacatgtctg aaatagaagc taggatcgcc
     1201 gcaaccacag gcaacggaca gccaagacgt agatccatcc aagacttgac tgtaactgga
     1261 acagaacctg gtcaggtgag cagtaggtca tccagtccca gtgtcagaat gattactacc
     1321 tcaggaccaa cctcagaaaa gccaactcga agtcatccat ggacccctga tgattccaca
     1381 gataccaatg gatcagataa ctccatccca atggcttatc ttacactgga tcaccaacta
     1441 cagcctctag caccgtgccc aaactccaaa gaatctatgg cagtgtttga acagcattgt
     1501 aaaatggcac aagaatatat gaaagttcaa acagaaattg cattgttatt acagagaaag
     1561 caagaactag ttgcagaact ggaccaggat gaaaaggacc agcaaaatac atctcgcctg
     1621 gtacaggaac ataaaaagct tttagatgaa aacaaaagcc tttctactta ctaccagcaa
     1681 tgcaaaaaac aactagaggt catcagaagt cagcagcaga aacgacaagg cacttcatga
//
