LOCUS       sequence-11197-e        2658 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 2658)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 2658)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-EXOSC10
FEATURES             Location/Qualifiers
     source          1..2658
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 atggcgccac ccagtacccg ggagcccagg gtcctgtcgg cgaccagcgc aaccaaatcc
       61 gacggagaga tggtgctgcc aggcttcccg gacgccgaca gctttgtgaa gtttgctctt
      121 gggtccgtgg tggcagtcac caaggcatct gggggcctac cacagtttgg cgatgagtat
      181 gatttttacc gaagttttcc tggcttccaa gcattttgcg aaacacaggg agacaggttg
      241 cttcagtgca tgagcagagt aatgcagtac catgggtgtc gcagcaacat taaggatcga
      301 agtaaagtga ctgagctgga agacaagttt gatttactag ttgatgccaa tgatgtaatt
      361 ctggagagag tgggtatttt actggatgaa gcctcaggtg taaacaagaa tcaacagcct
      421 gtcctccctg ccggcttgca ggtccccaaa acggtagtgt ccagctggaa ccgtaaggca
      481 gcagaatatg gcaaaaaagc aaaatctgaa actttccggc tgcttcatgc aaaaaatatc
      541 atccgacctc agctcaagtt tcgagagaag attgacaatt ccaacacacc atttcttcct
      601 aaaatcttca tcaaacccaa tgctcagaaa cctctccctc aagctctctc taaggaaagg
      661 cgggaacgcc cacaggatcg tcctgaggac ttggacgtcc cccctgcact ggctgatttc
      721 atccatcagc agagaaccca gcaggttgag caagacatgt ttgcacatcc ttatcaatat
      781 gaactaaatc actttacccc agcagatgca gtgcttcaaa agccacaacc ccagttatac
      841 agacctatag aagagacacc atgccatttc atatcctccc tggatgaact cgtggaactc
      901 aacgaaaagc tcttgaattg tcaggaattt gcagttgact tggagcacca ctcttacagg
      961 agcttcctgg gactgacctg cctgatgcaa atttctactc ggacggaaga cttcatcatt
     1021 gacaccctcg agcttcgaag tgacatgtac attctcaatg agagcctcac agacccagcc
     1081 atcgttaagg tctttcatgg tgctgattca gacatagaat ggctacagaa agactttggg
     1141 ttgtatgtag taaacatgtt tgatactcat caggcagcac gccttcttaa cctgggcagg
     1201 cactcactcg atcatctcct gaaactctac tgcaacgtgg actcaaacaa gcaatatcag
     1261 ctggctgatt ggagaatacg ccctctgccc gaggagatgc tcagctacgc ccgggatgac
     1321 acccattacc tgctatatat ctatgacaaa atgaggctgg agatgtggga gcgcggcaac
     1381 gggcagcccg tgcagctgca ggtggtgtgg caacggagca gggacatctg cctcaagaaa
     1441 ttcatcaaac ctatcttcac ggatgagtcc taccttgaac tctataggaa gcagaagaag
     1501 caccttaaca cacagcagtt gacagccttt cagctgctgt ttgcctggag ggataaaaca
     1561 gctcgcaggg aagatgaaag ttacggatat gtactgccaa accacatgat gctgaaaata
     1621 gctgaagaac tgcctaagga acctcagggc atcatagctt gctgcaaccc agtaccgccc
     1681 cttgtgcggc agcagatcaa cgaaatgcac cttttaatcc agcaggcccg agagatgccc
     1741 ctgctcaagt ctgaagttgc agccggagtg aagaagagcg gaccgctgcc cagtgctgag
     1801 agattggaga atgttctctt tggacctcac gactgctccc atgcccctcc ggatggctat
     1861 ccaatcatcc caaccagtgg atctgtgcca gttcagaagc aggcgagcct cttccctgat
     1921 gaaaaagaag ataacttgct gggtaccaca tgcctgattg ccacagctgt catcacgtta
     1981 tttaatgaac ctagtgctga agacagtaaa aagggtccat tgacagttgc acagaaaaaa
     2041 gcccagaaca tcatggagtc ctttgaaaat ccatttagga tgtttctgcc ctcactggga
     2101 caccgtgctc ccgtctctca ggcagcgaag ttcgatccat caaccaaaat ctatgaaatc
     2161 agcaaccgtt ggaagctggc ccaggtacaa gtacaaaaag actctaaaga agctgtcaag
     2221 aagaaggcag ctgagcaaac agctgcccgg gaacaggcaa aggaggcgtg caaagctgca
     2281 gcagaacagg ccatctccgt ccgacagcag gtcgtgctag aaaatgctgc aaagaagaga
     2341 gagcgagcaa caagcgaccc aaggaccaca gaacagaaac aagagaagaa acgactcaaa
     2401 atttccaaga agccaaagga cccagagcca ccagaaaaag agtttacgcc ttacgactac
     2461 agccagtcag acttcaaggc ttttgctgga aacagcaaat ccaaagtttc ttctcagttt
     2521 gatccaaata aacagacccc gtctggcaag aaatgcattg cagccaaaaa aattaaacag
     2581 tcggtgggaa acaaaagcat gtcctttcca actggaaagt cagacagagg cttcaggtac
     2641 aactggccac agagatag
//
