LOCUS       sequence-11199-e        1725 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 1725)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 1725)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-PKLR
FEATURES             Location/Qualifiers
     source          1..1725
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 atgtcgatcc aggagaacat atcatccctg cagcttcggt catgggtctc taagtcccaa
       61 agagacttag caaagtccat cctgattggg gctccaggag ggccagcggg gtatctgcgg
      121 cgggccagtg tggcccaact gacccaggag ctgggcactg ccttcttcca gcagcagcag
      181 ctgccagctg ctatggcaga caccttcctg gaacacctct gcctactgga cattgactcc
      241 gagcccgtgg ctgctcgcag taccagcatc attgccacca tcgggccagc atctcgctcc
      301 gtggagcgcc tcaaggagat gatcaaggcc gggatgaaca ttgcgcgact caacttctcc
      361 cacggctccc acgagtacca tgctgagtcc atcgccaacg tccgggaggc ggtggagagc
      421 tttgcaggtt ccccactcag ctaccggccc gtggccatcg ccctggacac caagggaccg
      481 gagatccgca ctgggatcct gcaggggggt ccagagtcgg aagtggagct ggtgaagggc
      541 tcccaggtgc tggtgactgt ggaccccgcg ttccggacgc gggggaacgc gaacaccgtg
      601 tgggtggact accccaatat tgtccgggtc gtgccggtgg ggggccgcat ctacattgac
      661 gacgggctca tctccctagt ggtccagaaa atcggcccag agggactggt gacccaagtg
      721 gagaacggcg gcgtcctggg cagccggaag ggcgtgaact tgccaggggc ccaggtggac
      781 ttgcccgggc tgtccgagca ggacgtccga gacctgcgct tcggggtgga gcatggggtg
      841 gacatcgtct ttgcctcctt tgtgcggaaa gccagcgacg tggctgccgt cagggctgct
      901 ctgggtccgg aaggacacgg catcaagatc atcagcaaaa ttgagaacca cgaaggcgtg
      961 aagaggtttg atgaaatcct ggaggtgagc gacggcatca tggtggcacg gggggaccta
     1021 ggcatcgaga tcccagcaga gaaggttttc ctggctcaga agatgatgat tgggcgctgc
     1081 aacttggcgg gcaagcctgt tgtctgtgcc acacagatgc tggagagcat gattaccaag
     1141 ccccggccaa cgagggcaga gacaagcgat gtcgccaatg ctgtgctgga tggggctgac
     1201 tgcatcatgc tgtcagggga gactgccaag ggcaacttcc ctgtggaagc ggtgaagatg
     1261 cagcatgcga ttgcccggga ggcagaggcc gcagtgtacc accggcagct gtttgaggag
     1321 ctacgtcggg cagcgccact aagccgtgat cccactgagg tcaccgccat tggtgctgtg
     1381 gaggctgcct tcaagtgctg tgctgctgcc atcattgtgc tgaccacaac tggccgctca
     1441 gcccagcttc tgtctcggta ccgacctcgg gcagcagtca ttgctgtcac ccgctctgcc
     1501 caggctgccc gccaggtcca cttatgccga ggagtcttcc ccttgcttta ccgtgaacct
     1561 ccagaagcca tctgggcaga tgatgtagat cgccgggtgc aatttggcat tgaaagtgga
     1621 aagctccgtg gcttcctccg tgttggagac ctggtgattg tggtgacagg ctggcgacct
     1681 ggctccggct acaccaacat catgagggtg ctaagcatat cctga
//
