LOCUS       sequence-11202-e        3117 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 3117)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 3117)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-BMPR2
FEATURES             Location/Qualifiers
     source          1..3117
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 atgacttcct cgctgcagcg gccctggcgg gtgccctggc taccatggac catcctgctg
       61 gtcagcactg cggctgcttc gcagaatcaa gaacggctat gtgcgtttaa agatccgtat
      121 cagcaagacc ttgggatagg tgagagtaga atctctcatg aaaatgggac aatattatgc
      181 tcgaaaggta gcacctgcta tggcctttgg gagaaatcaa aaggggacat aaatcttgta
      241 aaacaaggat gttggtctca cattggagat ccccaagagt gtcactatga agaatgtgta
      301 gtaactacca ctcctccctc aattcagaat ggaacatacc gtttctgctg ttgtagcaca
      361 gatttatgta atgtcaactt tactgagaat tttccacctc ctgacacaac accactcagt
      421 ccacctcatt catttaaccg agatgagaca ataatcattg ctttggcatc agtctctgta
      481 ttagctgttt tgatagttgc cttatgcttt ggatacagaa tgttgacagg agaccgtaaa
      541 caaggtcttc acagtatgaa catgatggag gcagcagcat ccgaaccctc tcttgatcta
      601 gataatctga aactgttgga gctgattggc cgaggtcgat atggagcagt atataaaggc
      661 tccttggatg agcgtccagt tgctgtaaaa gtgttttcct ttgcaaaccg tcagaatttt
      721 atcaacgaaa agaacattta cagagtgcct ttgatggaac atgacaacat tgcccgcttt
      781 atagttggag atgagagagt cactgcagat ggacgcatgg aatatttgct tgtgatggag
      841 tactatccca atggatcttt atgcaagtat ttaagtctcc acacaagtga ctgggtaagc
      901 tcttgccgtc ttgctcattc tgttactaga ggactggctt atcttcacac agaattacca
      961 cgaggagatc attataaacc tgcaatttcc catcgagatt taaacagcag aaatgtccta
     1021 gtgaaaaatg atggaacctg tgttattagt gactttggac tgtccatgag gctgactgga
     1081 aatagactgg tgcgcccagg ggaggaagat aatgcagcca taagcgaggt tggcactatc
     1141 agatatatgg caccagaagt gctagaagga gctgtgaact tgagggactg tgaatcagct
     1201 ttgaaacaag tagacatgta tgctcttgga ctaatctatt gggagatatt tatgagatgt
     1261 acagacctct tcccagggga atccgtacca gagtaccaga tggcttttca gacagaggtt
     1321 ggaaaccatc ccacttttga ggatatgcag gttctcgtgt ctagggaaaa acagagaccc
     1381 aagttcccag aagcctggaa agaaaatagc ctggcagtga ggtcactcaa ggagacaatc
     1441 gaagactgtt gggaccagga tgcagaggct cggcttactg cacagtgtgc tgaggaaagg
     1501 atggctgaac ttatgatgat ttgggaaaga aacaaatctg tgagcccaac agtcaatcca
     1561 atgtctactg ctatgcagaa tgaacgcaac ctgtcacata ataggcgtgt gccaaaaatt
     1621 ggtccttatc cagattattc ttcctcctca tacattgaag actctatcca tcatactgac
     1681 agcatcgtga agaatatttc ctctgagcat tctatgtcca gcacaccttt gactataggg
     1741 gaaaaaaacc gaaattcaat taactatgaa cgacagcaag cacaagctcg aatccccagc
     1801 cctgaaacaa gtgtcaccag cctctccacc aacacaacaa ccacaaacac cacaggactc
     1861 acgccaagta ctggcatgac tactatatct gagatgccat acccagatga aacaaatctg
     1921 cataccacaa atgttgcaca gtcaattggg ccaacccctg tctgcttaca gctgacagaa
     1981 gaagacttgg aaaccaacaa gctagaccca aaagaagttg ataagaacct caaggaaagc
     2041 tctgatgaga atctcatgga gcactctctt aaacagttca gtggcccaga cccactgagc
     2101 agtactagtt ctagcttgct ttacccactc ataaaacttg cagtagaagc aactggacag
     2161 caggacttca cacagactgc aaatggccaa gcatgtttga ttcctgatgt tctgcctact
     2221 cagatctatc ctctccccaa gcagcagaac cttcccaaga gacctactag tttgcctttg
     2281 aacaccaaaa attcaacaaa agagccccgg ctaaaatttg gcagcaagca caaatcaaac
     2341 ttgaaacaag tcgaaactgg agttgccaag atgaatacaa tcaatgcagc agaacctcat
     2401 gtggtgacag tcaccatgaa tggtgtggca ggtagaaacc acagtgttaa ctcccatgct
     2461 gccacaaccc aatatgccaa tgggacagta ctatctggcc aaacaaccaa catagtgaca
     2521 catagggccc aagaaatgtt gcagaatcag tttattggtg aggacacccg gctgaatatt
     2581 aattccagtc ctgatgagca tgagccttta ctgagacgag agcaacaagc tggccatgat
     2641 gaaggtgttc tggatcgtct tgtggacagg agggaacggc cactagaagg tggccgaact
     2701 aattccaata acaacaacag caatccatgt tcagaacaag atgttcttgc acagggtgtt
     2761 ccaagcacag cagcagatcc tgggccatca aagcccagaa gagcacagag gcctaattct
     2821 ctggatcttt cagccacaaa tgtcctggat ggcagcagta tacagatagg tgagtcaaca
     2881 caagatggca aatcaggatc aggtgaaaag atcaagaaac gtgtgaaaac tccctattct
     2941 cttaagcggt ggcgcccctc cacctgggtc atctccactg aatcgctgga ctgtgaagtc
     3001 aacaataatg gcagtaacag ggcagttcat tccaaatcca gcactgctgt ttaccttgca
     3061 gaaggaggca ctgctacaac catggtgtct aaagatatag gaatgaactg tctgtga
//
