LOCUS       sequence-11226-e        2949 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 2949)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 2949)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-EPHA3
FEATURES             Location/Qualifiers
     source          1..2949
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 atggattgtc agctctccat cctcctcctt ctcagctgct ctgttctcga cagcttcggg
       61 gaactgattc cgcagccttc caatgaagtc aatctactgg attcaaaaac aattcaaggg
      121 gagctgggct ggatctctta tccatcacat gggtgggaag agatcagtgg tgtggatgaa
      181 cattacacac ccatcaggac ttaccaggtg tgcaatgtca tggaccacag tcaaaacaat
      241 tggctgagaa caaactgggt ccccaggaac tcagctcaga agatttatgt ggagctcaag
      301 ttcactctac gagactgcaa tagcattcca ttggttttag gaacttgcaa ggagacattc
      361 aacctgtact acatggagtc tgatgatgat catggggtga aatttcgaga gcatcagttt
      421 acaaagattg acaccattgc agctgatgaa agtttcactc aaatggatct tggggaccgt
      481 attctgaagc tcaacactga gattagagaa gtaggtcctg tcaacaagaa gggattttat
      541 ttggcatttc aagatgttgg tgcttgtgtt gccttggtgt ctgtgagagt atacttcaaa
      601 aagtgcccat ttacagtgaa gaatctggct atgtttccag acacggtacc catggactcc
      661 cagtccctgg tggaggttag agggtcttgt gtcaacaatt ctaaggagga agatcctcca
      721 aggatgtact gcagtacaga aggcgaatgg cttgtaccca ttggcaagtg ttcctgcaat
      781 gctggctatg aagaaagagg ttttatgtgc caagcttgtc gaccaggttt ctacaaggca
      841 ttggatggta atatgaagtg tgctaagtgc ccgcctcaca gttctactca ggaagatggt
      901 tcaatgaact gcaggtgtga gaataattac ttccgggcag acaaagaccc tccatccatg
      961 gcttgtaccc gacctccatc ttcaccaaga aatgttatct ctaatataaa cgagacctca
     1021 gttatcctgg actggagttg gcccctggac acaggaggcc ggaaagatgt taccttcaac
     1081 atcatatgta aaaaatgtgg gtggaatata aaacagtgtg agccatgcag cccaaatgtc
     1141 cgcttcctcc ctcgacagtt tggactcacc aacaccacgg tgacagtgac agaccttctg
     1201 gcacatacta actacacctt tgagattgat gccgttaatg gggtgtcaga gctgagctcc
     1261 ccaccaagac agtttgctgc ggtcagcatc acaactaatc aggctgctcc atcacctgtc
     1321 ctgacgatta agaaagatcg gacctccaga aatagcatct ctttgtcctg gcaagaacct
     1381 gaacatccta atgggatcat attggactac gaggtcaaat actatgaaaa gcaggaacaa
     1441 gaaacaagtt ataccattct gagggcaaga ggcacaaatg ttaccatcag tagcctcaag
     1501 cctgacacta tatacgtatt ccaaatccga gcccgaacag ccgctggata tgggacgaac
     1561 agccgcaagt ttgagtttga aactagtcca gactctttct ccatctctgg tgaaagtagc
     1621 caagtggtca tgatcgccat ttcagcggca gtagcaatta ttctcctcac tgttgtcatc
     1681 tatgttttga ttgggaggtt ctgtggctat aagtcaaaac atggggcaga tgaaaaaaga
     1741 cttcattttg gcaatgggca tttaaaactt ccaggtctca ggacttatgt tgacccacat
     1801 acatatgaag accctaccca agctgttcat gagtttgcca aggaattgga tgccaccaac
     1861 atatccattg ataaagttgt tggagcaggt gaatttggag aggtgtgcag tggtcgctta
     1921 aaacttcctt caaaaaaaga gatttcagtg gccattaaga ccctgaaagt tggctacaca
     1981 gaaaagcaga ggagagactt cctgggagaa gcaagcatta tgggacagtt tgaccacccc
     2041 aatatcattc gactggaagg agttgttacc aaaagtaagc cagttatgat tgtcacagaa
     2101 tacatggaga atggttcctt ggatagtttc ctacgtaaac acgatgccca gtttactgtc
     2161 attcagctag tggggatgct tcgagggata gcatctggca tgaagtacct gtcagacatg
     2221 ggctatgttc accgagacct cgctgctcgg aacatcttga tcaacagtaa cttggtgtgt
     2281 aaggtttctg atttcggact ttcgcgtgtc ctggaggatg acccagaagc tgcttataca
     2341 acaagaggag ggaagatccc aatcaggtgg acatcaccag aagctatagc ctaccgcaag
     2401 ttcacgtcag ccagcgatgt atggagttat gggattgttc tctgggaggt gatgtcttat
     2461 ggagagagac catactggga gatgtccaat caggatgtaa ttaaagctgt agatgagggc
     2521 tatcgactgc caccccccat ggactgccca gctgccttgt atcagctgat gctggactgc
     2581 tggcagaaag acaggaacaa cagacccaag tttgagcaga ttgttagtat tctggacaag
     2641 cttatccgga atcccggcag cctgaagatc atcaccagtg cagccgcaag gccatcaaac
     2701 cttcttctgg accaaagcaa tgtggatatc actaccttcc gcacaacagg tgactggctt
     2761 aatggtgtct ggacagcaca ctgcaaggaa atcttcacgg gtgtggagta cagttcttgt
     2821 gacacaatag ccaagatttc cacagatgac atgaaaaagg ttggtgtcac cgtggttggg
     2881 ccacagaaga agatcatcag tagcattaaa gctctagaaa cgcaatcaaa gaatggccca
     2941 gttcccgtg
//
