LOCUS       sequence-11230-e        3396 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 3396)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 3396)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-JAK2
FEATURES             Location/Qualifiers
     source          1..3396
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 atgggaatgg cctgccttac gatgacagaa atggagggaa catccacctc ttctatatat
       61 cagaatggtg atatttctgg aaatgccaat tctatgaagc aaatagatcc agttcttcag
      121 gtgtatcttt accattccct tgggaaatct gaggcagatt atctgacctt tccatctggg
      181 gagtatgttg cagaagaaat ctgtattgct gcttctaaag cttgtggtat cacacctgtg
      241 tatcataata tgtttgcttt aatgagtgaa acagaaagga tctggtatcc acccaaccat
      301 gtcttccata tagatgagtc aaccaggcat aatgtactct acagaataag attttacttt
      361 cctcgttggt attgcagtgg cagcaacaga gcctatcggc atggaatatc tcgaggtgct
      421 gaagctcctc ttcttgatga ctttgtcatg tcttacctct ttgctcagtg gcggcatgat
      481 tttgtgcacg gatggataaa agtacctgtg actcatgaaa cacaggaaga atgtcttggg
      541 atggcagtgt tagatatgat gagaatagcc aaagaaaacg atcaaacccc actggccatc
      601 tataactcta tcagctacaa gacattctta ccaaaatgta ttcgagcaaa gatccaagac
      661 tatcatattt tgacaaggaa gcgaataagg tacagatttc gcagatttat tcagcaattc
      721 agccaatgca aagccactgc cagaaacttg aaacttaagt atcttataaa tctggaaact
      781 ctgcagtctg ccttctacac agagaaattt gaagtaaaag aacctggaag tggtccttca
      841 ggtgaggaga tttttgcaac cattataata actggaaacg gtggaattca gtggtcaaga
      901 gggaaacata aagaaagtga gacactgaca gaacaggatt tacagttata ttgcgatttt
      961 cctaatatta ttgatgtcag tattaagcaa gcaaaccaag agggttcaaa tgaaagccga
     1021 gttgtaacta tccataagca agatggtaaa aatctggaaa ttgaacttag ctcattaagg
     1081 gaagctttgt ctttcgtgtc attaattgat ggatattata gattaactgc agatgcacat
     1141 cattacctct gtaaagaagt agcacctcca gccgtgcttg aaaatataca aagcaactgt
     1201 catggcccaa tttcgatgga ttttgccatt agtaaactga agaaagcagg taatcagact
     1261 ggactgtatg tacttcgatg cagtcctaag gactttaata aatatttttt gacttttgct
     1321 gtcgagcgag aaaatgtcat tgaatataaa cactgtttga ttacaaaaaa tgagaatgaa
     1381 gagtacaacc tcagtgggac aaagaagaac ttcagcagtc ttaaagatct tttgaattgt
     1441 taccagatgg aaactgttcg ctcagacaat ataattttcc agtttactaa atgctgtccc
     1501 ccaaagccaa aagataaatc aaaccttcta gtcttcagaa cgaatggtgt ttctgatgta
     1561 ccaacctcac caacattaca gaggcctact catatgaacc aaatggtgtt tcacaaaatc
     1621 agaaatgaag atttgatatt taatgaaagc cttggccaag gcacttttac aaagattttt
     1681 aaaggcgtac gaagagaagt aggagactac ggtcaactgc atgaaacaga agttctttta
     1741 aaagttctgg ataaagcaca cagaaactat tcagagtctt tctttgaagc agcaagtatg
     1801 atgagcaagc tttctcacaa gcatttggtt ttaaattatg gagtatgtgt ctgtggagac
     1861 gagaatattc tggttcagga gtttgtaaaa tttggatcac tagatacata tctgaaaaag
     1921 aataaaaatt gtataaatat attatggaaa cttgaagttg ctaaacagtt ggcatgggcc
     1981 atgcattttc tagaagaaaa cacccttatt catgggaatg tatgtgccaa aaatattctg
     2041 cttatcagag aagaagacag gaagacagga aatcctcctt tcatcaaact tagtgatcct
     2101 ggcattagta ttacagtttt gccaaaggac attcttcagg agagaatacc atgggtacca
     2161 cctgaatgca ttgaaaatcc taaaaattta aatttggcaa cagacaaatg gagttttggt
     2221 accactttgt gggaaatctg cagtggagga gataaacctc taagtgctct ggattctcaa
     2281 agaaagctac aattttatga agataggcat cagcttcctg caccaaagtg ggcagaatta
     2341 gcaaacctta taaataattg tatggattat gaaccagatt tcaggccttc tttcagagcc
     2401 atcatacgag atcttaacag tttgtttact ccagattatg aactattaac agaaaatgac
     2461 atgttaccaa atatgaggat aggtgcccta gggttttctg gtgcctttga agaccgggat
     2521 cctacacagt ttgaagagag acatttgaaa tttctacagc aacttggcaa gggtaatttt
     2581 gggagtgtgg agatgtgccg gtatgaccct ctacaggaca acactgggga ggtggtcgct
     2641 gtaaaaaagc ttcagcatag tactgaagag cacctaagag actttgaaag ggaaattgaa
     2701 atcctgaaat ccctacagca tgacaacatt gtaaagtaca agggagtgtg ctacagtgct
     2761 ggtcggcgta atctaaaatt aattatggaa tatttaccat atggaagttt acgagactat
     2821 cttcaaaaac ataaagaacg gatagatcac ataaaacttc tgcagtacac atctcagata
     2881 tgcaagggta tggagtatct tggtacaaaa aggtatatcc acagggatct ggcaacgaga
     2941 aatatattgg tggagaacga gaacagagtt aaaattggag attttgggtt aaccaaagtc
     3001 ttgccacaag acaaagaata ctataaagta aaagaacctg gtgaaagtcc catattctgg
     3061 tatgctccag aatcactgac agagagcaag ttttctgtgg cctcagatgt ttggagcttt
     3121 ggagtggttc tgtatgaact tttcacatac attgagaaga gtaaaagtcc accagcggaa
     3181 tttatgcgta tgattggcaa tgacaaacaa ggacagatga tcgtgttcca tttgatagaa
     3241 cttttgaaga ataatggaag attaccaaga ccagatggat gcccagatga gatctatatg
     3301 atcatgacag aatgctggaa caataatgta aatcaacgcc cctcctttag ggatctagct
     3361 cttcgagtgg atcaaataag ggataacatg gctgga
//
