LOCUS       sequence-11233-e        1977 bp    DNA     linear   UNA 15-DEC-2025
DEFINITION  natural linear DNA
ACCESSION   .
VERSION     .
KEYWORDS    .
SOURCE      natural DNA sequence
  ORGANISM  unspecified
REFERENCE   1  (bases 1 to 1977)
  AUTHORS   Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA,
            Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, 
            Hieronymus H, Murray RR, Salehi-Ashtiani K, Hill DE, Vidal M, Zhao 
            JJ, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM,
            Root DE, Roberts TM, Golub T, Flaherty KT, Dummer R, Weber BL, 
            Sellers WR, Schlegel R, Wargo JA, Hahn WC, Garraway LA
  TITLE     COT drives resistance to RAF inhibition through MAP kinase pathway 
            reactivation.
  JOURNAL   Nature. 2010 Dec 16;468(7326):968-72. doi: 10.1038/nature09627
  PUBMED    21107320
REFERENCE   2  (bases 1 to 1977)
  AUTHORS   .
  TITLE     Direct Submission
  JOURNAL   Exported Dec 15, 2025 from SnapGene Server 8.0.1
            https://www.snapgene.com
COMMENT     SGRef: number: 1; type: "Journal Article"; doi: "10"; journalName: 
            "Nature"; date: "2010-12-16- 16"; volume: "468"; issue: "7326"; 
            pages: "968-72"
COMMENT     Sequence Label: pDONR223-BTK
FEATURES             Location/Qualifiers
     source          1..1977
                     /mol_type="genomic DNA"
                     /organism="unspecified"
ORIGIN
        1 atggccgcag tgattctgga gagcatcttt ctgaagcgat cccaacagaa aaagaaaaca
       61 tcacctctaa acttcaagaa gcgcctgttt ctcttgaccg tgcacaaact ctcctactat
      121 gagtatgact ttgaacgtgg gagaagaggc agtaagaagg gttcaataga tgttgagaag
      181 atcacttgtg ttgaaacagt ggttcctgaa aaaaatcctc ctccagaaag acagattccg
      241 agaagaggtg aagagtccag tgaaatggag caaatttcaa tcattgaaag gttcccttat
      301 cccttccagg ttgtatatga tgaagggcct ctctacgtct tctccccaac tgaagaacta
      361 aggaagcggt ggattcacca gctcaaaaac gtaatccggt acaacagtga tctggttcag
      421 aaatatcacc cttgcttctg gatcgatggg cagtatctct gctgctctca gacagccaaa
      481 aatgctatgg gctgccaaat tttggagaac aggaatggaa gcttaaaacc tgggagttct
      541 caccggaaga caaaaaagcc tcttccccca acgcctgagg aggaccagat cttgaaaaag
      601 ccactaccgc ctgagccagc agcagcacca gtctccacaa gtgagctgaa aaaggttgtg
      661 gccctttatg attacatgcc aatgaatgca aatgatctac agctgcggaa gggtgatgaa
      721 tattttatct tggaggaaag caacttacca tggtggagag cacgagataa aaatgggcag
      781 gaaggctaca ttcctagtaa ctatgtcact gaagcagaag actccataga aatgtatgag
      841 tggtattcca aacacatgac tcggagtcag gctgagcaac tgctaaagca agaggggaaa
      901 gaaggaggtt tcattgtcag agactccagc aaagctggca aatatacagt gtctgtgttt
      961 gctaaatcca caggggaccc tcaaggggtg atacgtcatt atgttgtgtg ttccacacct
     1021 cagagccagt attacctggc tgagaagcac cttttcagca ccatccctga gctcattaac
     1081 taccatcagc acaactctgc aggactcata tccaggctca aatatccagt gtctcaacaa
     1141 aacaagaatg caccttccac tgcaggcctg ggatacggat catgggaaat tgatccaaag
     1201 gacctgacct tcttgaagga gctggggact ggacaatttg gggtagtgaa gtatgggaaa
     1261 tggagaggcc agtacgacgt ggccatcaag atgatcaaag aaggctccat gtctgaagat
     1321 gaattcattg aagaagccaa agtcatgatg aatctttccc atgagaagct ggtgcagttg
     1381 tatggcgtct gcaccaagca gcgccccatc ttcatcatca ctgagtacat ggccaatggc
     1441 tgcctcctga actacctgag ggagatgcgc caccgcttcc agactcagca gctgctagag
     1501 atgtgcaagg atgtctgtga agccatggaa tacctggagt caaagcagtt ccttcaccga
     1561 gacctggcag ctcgaaactg tttggtaaac gatcaaggag ttgttaaagt atctgatttc
     1621 ggcctgtcca ggtatgtcct ggatgatgaa tacacaagct cagtaggctc caaatttcca
     1681 gtccggtggt ccccaccgga agtcctgatg tatagcaagt tcagcagcaa atctgacatt
     1741 tgggcttttg gggttttgat gtgggaaatt tactccctgg ggaagatgcc atatgagaga
     1801 tttactaaca gtgagactgc tgaacacatt gcccaaggcc tacgtctcta caggcctcat
     1861 ctggcttcag agaaggtata taccatcatg tacagttgct ggcatgagaa agcagatgag
     1921 cgtcccactt tcaaaattct tctgagcaat attctagatg tcatggatga agaatcc
//
